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  • Generic Name: (oxaprozin)
    Other Brands: N/A
  • Last Revised: 06/2016
    • What is this medication and its most common uses?

      Daypro is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve signs and symptoms of osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Daypro blocks a substance in your body that is involved in causing inflammation and pain in parts of the body where there is arthritis.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Daypro may help relieve your arthritis symptoms, such as pain, swelling, and stiffness.

      When: In studies, several days of therapy were needed for the drug to reach its full effects.

      How do I know it is working?

      You may feel relief in your arthritis symptoms after you start taking Daypro. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Daypro can increase the risk of a heart attack or stroke that can be life threatening. This risk may happen early in treatment and may increase with increasing doses and with longer use of NSAIDs.

      Do not take Daypro right before or after a heart surgery called a coronary artery bypass graft (CABG).

      Daypro can also increase the risk of bleeding, ulcers, and tears (perforation) of the esophagus (tube leading from the mouth to the stomach), stomach, and intestines. This can happen anytime during use, without warning symptoms, and may be life threatening. The risk of getting an ulcer or bleeding increases with past history of stomach ulcers, or stomach or intestinal bleeding with use of NSAIDs; taking certain steroid medicines, blood thinners, or certain antidepressants; increasing doses or longer use of NSAIDs; smoking; drinking alcohol; older age; poor health; advanced liver disease; or bleeding problems.

      More common side effects may include: constipation, diarrhea, heartburn, nausea, rash.

      Less common side effects may include:

      Liver problems with symptoms such as nausea, tiredness, weakness, itching, yellowing of your skin or the whites of your eyes, right upper stomach pain, and flu-like symptoms.

      Serious allergic reactions with symptoms such as skin rash, blisters, fever, itching, trouble breathing, or swelling of your face or throat.

      Harm to your unborn baby. Tell your healthcare provider immediately if you are pregnant or plan to become pregnant.

      Daypro may cause high blood pressure, photosensitivity (increased sensitivity to sunlight), kidney problems, anemia (low red blood cell counts), high blood potassium levels, or unexplained weight gain or swelling.

    • Who should not take this medication?

      Do not take Daypro if you are allergic to it or any of its ingredients.

      Do not take Daypro if you have had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID (such as ibuprofen or naproxen).

      Do not take Daypro right before or after a heart bypass surgery.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Daypro. Also, talk to your healthcare provider about your complete medical history, especially if you have asthma, high blood pressure or heart failure, kidney or liver problems, or a history of ulcers or bleeding in your stomach or intestines, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Osteoarthritis and Rheumatoid Arthritis

      Adults: The usual dose is 1200 milligrams (mg) (two 600-mg tablets) once a day.

      Juvenile Rheumatoid Arthritis

      Children 6-16 years: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her weight.

      If you have kidney problems or low body weight, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Take Daypro exactly as prescribed by your healthcare provider. Do not change your dose without first talking to your healthcare provider.

    • What should I avoid while taking this medication?

      Do not take aspirin or other NSAIDs in combination with Daypro without first talking to your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Daypro is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Daypro may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Daypro can harm your unborn baby if you take it during the late stage of your pregnancy. Do not take Daypro if you are in the late stage of your pregnancy (≥30 weeks). The effects of Daypro during early pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Daypro, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature. Protect from light.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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