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  • Generic Name: (methylphenidate)
    Other Brands: N/A
  • Last Revised: 09/2015
    • What is this medication and its most common uses?

      Daytrana is a medicine used to treat attention-deficit hyperactivity disorder (ADHD).

      Daytrana is a federally controlled substance because it has abuse potential.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Daytrana is a patch that you apply to the skin on your hip. Daytrana works by changing the amount of certain chemicals in your brain, thereby improving your symptoms of ADHD.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Daytrana is an important part of a total treatment program for people with ADHD that may include counseling or other therapies. Daytrana may help increase attention and decrease impulsiveness and hyperactivity in people with ADHD.

      When: Daytrana may start working 2 hours after the patch is applied.

      How do I know it is working?

      You may start to notice an improvement in your symptoms. This is a good indicator that your medication is working. Your healthcare provider may ask you questions from time to time to assess how well your medicine is working and to check for improvement of your condition.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Daytrana is a federally controlled substance because it can be abused or lead to dependence. Keep Daytrana in a safe place to prevent misuse and abuse. Selling or giving away Daytrana may harm others, and is against the law.

      Adolescents 13-17 years

      More common side effects may include: loss of appetite, nausea, sleeplessness, weight loss, dizziness, stomach pain, redness at application site.

      Children 6-12 years

      More common side effects may include: loss of appetite, sleeplessness, nausea, vomiting, weight loss, tics (repeated movements or sounds that cannot be controlled), mood swings.

      Less common side effects of Daytrana may include:

      Sudden death in people who have heart problems or heart defects; stroke and heart attack in adults; increased blood pressure and heart rate with symptoms such as chest pain, shortness of breath, or fainting.

      Mental problems with symptoms such as new or worsening behavior and thought problems, bipolar illness, aggressive behavior, or hostility. Children and teenagers may also begin to hear voices, believe in things that are not true, or become suspicious.

      Slowing of growth (height and weight) in children.

      Seizures, mainly in people with a history of seizures.

      Eyesight changes or blurred vision.

      Prolonged and painful erections.

      Persistent loss of skin color at or around the patch application site.

      Circulation problems in your fingers or toes, with symptoms such as feeling numb, cool, painful, or changing color (such as from pale to blue to red).

      Allergic skin reactions may occur while you are using Daytrana. Stop using Daytrana and tell your healthcare provider right away if you develop redness, swelling, or blisters that do not improve within 48 hours or spread beyond the patch site.

    • Who should not take this medication?

      Do not use Daytrana if you are allergic to it or any of its ingredients.

      Do not use Daytrana if you are very anxious, tense, or agitated.

      Do not use Daytrana if you have glaucoma (high pressure in the eye), tics, Tourette's syndrome (a brain disorder characterized by involuntary movements and vocalizations called tics), or have a family history of Tourette's syndrome.

      Do not use Daytrana if you are taking an antidepressant medication called a monoamine oxidase inhibitor (MAOI) (such as phenelzine or selegiline) or have taken any within the past 14 days.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Daytrana. Also, talk to your healthcare provider about your complete medical history, including heart problems, heart defects, high blood pressure, mental problems (such as psychosis, mania, bipolar disorder, or depression), or a family history of these problems; seizures; circulation problems in your fingers and toes; skin problems such as eczema or psoriasis; any previous skin reactions to soaps, lotions, makeup, or adhesives (glues); history and/or family history of vitiligo (a condition that causes the skin to lose color in blotches); or have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Children and adolescents 6-17 years: Apply 1 patch to your hip once a day. Your healthcare provider will prescribe the appropriate dose for you based on your previous ADHD medication.

    • How should I take this medication?

      Use Daytrana exactly as prescribed by your healthcare provider. Do not change your dose or stop using Daytrana without first talking to your healthcare provider.

      Apply Daytrana to your hip 2 hours before an effect is needed. Do not wear Daytrana longer than 9 hours a day.

      Apply Daytrana to a different hip each day. Do not cut the patches.

      If you are a parent or caregiver, you can apply and remove Daytrana for your child if your child is not responsible enough to do so.

      Contact with water while bathing, swimming, or showering can make the patch not stick well or make it fall off. If your patch falls off, do not touch the sticky side of the patch with your fingers. You can apply a new patch to a different area on the same hip. If you have to replace the patch that has fallen off, the total wear time for the first and second patch should not be more than a total of 9 hours in one day. Do not reapply the same patch that fell off.

    • What should I avoid while taking this medication?

      Do not put any medicine, cream, or lotion on your hip before you apply the Daytrana patch. Medicines, creams, or lotions may affect how the patch sticks to your skin and how the medicine is absorbed from the patch.

      Do not use bandages, tape, or other household adhesives to hold the patch onto your skin.

      Avoid hair dryers, heating pads, electric blankets, heated water beds, or other heat sources while wearing a Daytrana patch. Too much medicine can pass into your body and cause serious side effects.

      Do not drive or operate machinery until you know how Daytrana affects you.

    • What are the possible food and drug interactions associated with this medication?

      If Daytrana is used with other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Daytrana with the following: blood pressure medications, blood thinners (such as warfarin), certain antidepressants known as tricyclic antidepressants (such as imipramine, clomipramine, or desipramine) or selective serotonin reuptake inhibitors (SSRIs) (such as fluoxetine or sertraline), or seizure medications (such as phenobarbital, phenytoin, or primidone).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of using Daytrana during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you forget to apply a patch in the morning, you may apply the patch later in the day. You should remove the patch at the usual time of the day to lower the chance of side effects later in the day.

    • How should I store this medication?

      Store at room temperature. Do not store in the refrigerator or freezer. Keep the patches unopened until you are ready to use them. Use or discard the patches within 2 months after you opened the sealed tray or outer pouch.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
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