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  • Generic Name: (desmopressin acetate)
    Other Brands: N/A
  • Last Revised: 01/2016
    • What is this medication and its most common uses?

      DDAVP rhinal tube is a medicine used to manage a type of diabetes called diabetes insipidus. DDAVP rhinal tube is also used to manage excessive thirst and production of urine following a head trauma or surgery. This medicine is administered into the nose through a soft, flexible plastic rhinal tube.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      DDAVP rhinal tube works by replacing vasopressin (a hormone that is normally produced in the body to help balance the amount of water and sodium [salt]), thereby improving your symptoms.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: DDAVP rhinal tube has been shown to decrease urinary frequency.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use DDAVP rhinal tube exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may feel an improvement in your symptoms after you start using DDAVP rhinal tube. Your healthcare provider may ask you a series of questions from time to time that will help assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: headache, runny nose, dizziness.

      Less common side effects may include:

      Low blood sodium levels, with symptoms such as headache, nausea, vomiting, weight gain, restlessness, tiredness, disorientation, depressed reflexes, loss of appetite, irritability, muscle weakness, muscle spasms or cramps, or abnormal mental status (including hallucinations).

    • Who should not take this medication?

      Do not use DDAVP rhinal tube if you are allergic to it or any of its ingredients.

      Do not use DDAVP rhinal tube if you have kidney problems.

      Do not use DDAVP rhinal tube if you have or have had low blood sodium levels in your body.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with DDAVP rhinal tube. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or heart problems; high blood pressure; cystic fibrosis; scarring, swelling, or any other disease in your nose; or if you drink excessive amounts of water.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The usual dose is 0.1 to 0.4 milliliters (mL) a day, either as a single dose or divided into two or three doses, as directed by your healthcare provider.

      Children 3 months-12 years: The usual dose is 0.05 to 0.3 mL a day, either as a single dose or divided into two doses, as directed by your healthcare provider.

      Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

    • How should I take this medication?

      Use DDAVP rhinal tube exactly as prescribed by your healthcare provider. Do not use it more often or stop using DDAVP rhinal tube without first talking to your healthcare provider.

      Please review the instructions that came with your prescription on how to properly use DDAVP rhinal tube.

      Always follow your healthcare provider's instructions regarding fluid intake while using DDAVP rhinal tube.

    • What should I avoid while taking this medication?

      Do not drink excessive amounts of water or other fluids while you are using DDAVP rhinal tube.

    • What are the possible food and drug interactions associated with this medication?

      If DDAVP rhinal tube is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining DDAVP rhinal tube with the following: carbamazepine, certain antidepressants (such as amitriptyline or sertraline), chlorpromazine, lamotrigine, narcotic painkillers (such as oxycodone or hydrocodone), or nonsteroidal anti-inflammatory drugs (NSAIDS) (such as ibuprofen or naproxen).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of DDAVP rhinal tube during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of DDAVP rhinal tube, use it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not use two doses at once.

    • How should I store this medication?

      Store bottles in the refrigerator.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.