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  • Generic Name: (prasugrel)
    Other Brands: N/A
  • Last Revised: 08/2016
    • What is this medication and its most common uses?

      Effient is a medicine used to treat people who have had a heart attack or severe chest pain due to heart problems, and have been treated with a procedure called angioplasty (a procedure to open the blood vessels that supply blood to the heart).



    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Blood clots form when certain blood cells, called platelets, clump together. Effient works by preventing platelets from sticking together and forming blood clots.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Effient, in combination with aspirin, helps lower your chance of having another serious problem with your heart or blood vessels, such as another heart attack, a stroke, or blood clots in your stent.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Effient exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider will monitor you regularly to check how well this medication is working.


    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Effient can cause bleeding that can be serious and sometimes life-threatening. Your risk of bleeding while taking Effient may be higher if you also have had trauma (such as an accident or surgery); have stomach or intestine bleeding that is recent or keeps coming back; have a stomach ulcer; have liver or kidney problems; weigh less than 132 pounds; or if you take other medicines that increase your risk of bleeding (such as heparin, nonsteroidal anti-inflammatory drugs [NSAIDs] [such as ibuprofen or naproxen], warfarin, or other medicines used to prevent or treat blood clots).

      Call your healthcare provider right away if you experience any signs or symptoms of bleeding, such as unexpected bleeding or bleeding that lasts a long time, severe or uncontrollable bleeding, pink or brown urine, red or black stool (looks like tar), bruises that develop without a known cause or grow in size, coughing up blood or blood clots, or vomiting blood or vomit that looks like coffee grounds.

      More common side effects may include: bleeding.

      Less common side effects may include:

      Thrombotic thrombocytopenic purpura (a condition in which blood clots form in the blood vessels and can occur all over the body), with symptoms such as purplish spots on your skin or in your mouth; paleness or jaundice (yellowing of the skin or whites of the eyes); tiredness or weakness; fever; fast heartbeat or shortness of breath; headache, speech changes, confusion, coma, stroke, or seizure; low amount of urine or urine that is pink or has blood in it; abdominal (stomach area) pain, nausea, vomiting, or diarrhea; or vision changes.

      Serious allergic reactions, with symptoms such as hives; swelling of your face, lips, throat, or in or around your mouth; trouble breathing or swallowing; chest pain or pressure; or dizziness or fainting.


    • Who should not take this medication?

      Do not take Effient if you are allergic to it or any of its ingredients.

      Do not take Effient if you currently have abnormal bleeding (such as stomach or intestinal bleeding, or bleeding in your head).

      Do not take Effient if you have had a stroke or a "mini-stroke" (also known as transient ischemic attack or TIA).

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Effient. Also, talk to your healthcare provider about your complete medical history, especially if you have bleeding, liver, or kidney problems; have a history of stomach ulcers, colon polyps (non-cancerous growths on the surface of the colon), diverticulosis (a condition in which pockets form in the large intestine), or a stroke or a "mini-stroke"; had any recent severe injury or surgery; plan to have surgery (such as heart bypass) or a dental procedure; or are pregnant, breastfeeding, or planning to become pregnant.



    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 10 milligrams (mg) once a day. Your healthcare provider will give you a single 60-mg dose before having you take 10 mg a day.

      If your body weight is low, your healthcare provider may adjust your dose appropriately.

      It is important that you do not stop taking this medication without talking to your healthcare provider. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.


    • How should I take this medication?

      Take Effient exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Effient without first talking to your healthcare provider.

      Take Effient with or without food.

      Take Effient with aspirin as instructed by your healthcare provider.

      Call your healthcare provider right away if you fall or injure yourself, especially if you hit your head.




    • What should I avoid while taking this medication?

      Do not stop taking Effient without first talking to your healthcare provider. Stopping Effient earlier than recommended may increase your risk of heart problems.

    • What are the possible food and drug interactions associated with this medication?

      If Effient is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Effient with the following: heparin, NSAIDs, or warfarin.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Effient during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.



    • What should I do if I miss a dose of this medication?

      If you miss a dose of Effient, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at the same time unless your healthcare provider tells you to.

    • How should I store this medication?

      Store at room temperature. Protect from moisture.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.