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Factive is an antibiotic used to treat certain bacterial infections, including bronchitis and pneumonia.
How does this medication work?
Factive works by stopping the growth of bacteria, thereby treating your infection.
Do not take Factive to treat viral infections (such as the common cold). Factive should only be used to treat bacterial infections.
What are the beneficial effects of this medication and when should I begin to have results?
What: In studies, most people being treated with Factive were shown to be infection-free at their follow-up visit.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Factive exactly as your healthcare provider has prescribed for the full course of treatment, even if your symptoms improve earlier.
How do I know it is working?
You may start to notice an improvement in your symptoms. This is a good indicator that your medication is working. Your healthcare provider may ask you questions and order tests to assess how well your infection is being treated.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Factive can cause tendon (tough cords of tissue that connect muscles to bones) rupture or swelling of the tendon. Tendon problems can happen in people of all ages who take Factive. Some tendon problems include pain, swelling, tears, and inflammation of tendons including the back of the ankle (Achilles), shoulder, hand, or other tendon sites. Tendon rupture or swelling can happen within hours or days of taking Factive and has happened up to several months after people finished taking their medicine. The risk of getting tendon problems while taking Factive is higher if you are over 60 years of age; are taking steroid medicines (such as prednisone); or have had a kidney, heart, or lung transplant. Other reasons that can increase your risk of tendon problems can include physical activity or exercise, kidney failure, and tendon problems in the past (such as in people with rheumatoid arthritis). Tendon problems can happen in people who do not have these risk factors when they take Factive. Stop taking Factive and get medical help right away at the first sign of tendon pain, swelling, or inflammation; if you hear or feel a snap or pop in a tendon area; if you have bruising right after an injury in a tendon area; or if you are unable to move the affected area or bear weight.
Damage to the nerves in the arms, hands, legs, or feet can happen in people who take Factive. Stop taking Factive and talk to your healthcare provider right away if you get any of the following symptoms in your arms, hands, legs, or feet: pain, burning, tingling, numbness, or weakness.
Factive may cause central nervous system (CNS) effects (including seizures). Tell your healthcare provider if you have a history of seizures before you start taking Factive. CNS effects may happen as soon as after taking the first dose of Factive. Talk to your healthcare provider right away if you experience seizures, tremors (shaking), confusion, depression, trouble sleeping, nightmares, or suicidal thoughts or acts; hear voices, see things, or sense things that are not there; or feel restless, anxious or nervous, dizzy, or paranoid (more suspicious).
Factive can cause worsening of myasthenia gravis (a disease characterized by long-lasting fatigue and muscle weakness) symptoms. Tell your healthcare provider if you have a history of myasthenia gravis before you start taking Factive. Call your healthcare provider right away if you develop worsening muscle weakness or breathing problems.
More common side effects may include: diarrhea, rash, nausea, headache, stomach pain, vomiting, dizziness.
Less common side effects may include:
Rare heart problem known as prolongation of the QT interval (very fast or abnormal heartbeat), with symptoms such as changes in heartbeat or fainting. The chance of this happening is higher in people who are elderly, have a family history of prolonged QT interval, have low blood potassium levels, or who take antiarrhythmics (certain medicines to control heart rhythm).
Serious allergic reactions, with symptoms such as hives; trouble breathing or swallowing; swelling of the face, lips, or tongue; throat tightness or hoarseness; rapid heartbeat; or fainting.
Intestinal infection that can happen 2 or more months after you have finished your antibiotic. Symptoms may include watery diarrhea, diarrhea that does not go away, or bloody stools. You may have stomach cramps and a fever.
Skin rash. This may happen more often with Factive in women (especially those who take hormone replacement therapy), people under 40 years of age, and people who take Factive for longer than 5 years.
Factive may also cause sensitivity to sunlight and changes in liver function blood tests.
Do not take Factive if you are allergic to it, any of its ingredients, or similar antibiotics (such as ciprofloxacin or levofloxacin).
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Factive. Also, talk to your healthcare provider about your complete medical history, especially if you: have tendon, nerve, joint, or kidney problems; have myasthenia gravis; have CNS problems (such as seizures); have low blood potassium or magnesium levels; have a slow heartbeat; have or anyone in your family has an irregular heartbeat (especially prolonged QT interval); are pregnant; plan to become pregnant; or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended dose is one 320-milligram (mg) tablet a day. Your healthcare provider will tell you how long to take Factive, based on the type of infection being treated.
If you have kidney problems, your healthcare provider may adjust your dose appropriately.
Take Factive exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Factive without first talking to your healthcare provider.
Factive should be swallowed whole with plenty of fluids.
Factive may be taken with or without food.
Take Factive either three hours before or two hours after you take any of these medicines: didanosine; sucralfate; or antacids, multivitamins, or other products that contain magnesium, aluminum, iron, or zinc.
Do not drive, operate machinery, or engage in other activities that require mental alertness or coordination until you know how Factive affects you.
Do not expose your skin to sunlamps or tanning beds, and try to limit your time in the sun, as Factive can make your skin sensitive to the sun and the light from sunlamps and tanning beds. If you need to be outdoors, use sunscreen and wear a hat and loose-fitting clothes that protect your skin from the sun.
Do not skip doses. Skipping doses or not completing the full course of Factive can decrease its effectiveness and can lead to the growth of bacteria that are resistant to the effects of Factive.
If Factive is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Factive with the following: antacids, multivitamins, or other products that contain magnesium, aluminum, iron, or zinc; antiarrhythmics; antipsychotic medicines; blood thinners (such as warfarin); certain antidepressant medicines; didanosine; probenecid; steroid medicines; or sucralfate.
The effects of Factive during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Factive, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature. Protect from light.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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