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  • Generic Name: (ethinyl estradiol/norethindrone acetate)
    Other Brands: N/A
  • Last Revised: 11/2014
    • What is this medication and its most common uses?

      Femhrt is a medicine used after menopause to reduce hot flashes and help reduce your chances of getting osteoporosis (thin, weak bones).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Menopausal women have lower levels of estrogen hormones in their bodies. Femhrt works by providing the body with estrogen.

      What are the beneficial effects of this medication and when should I begin to have results?


      Hot Flashes: In a clinical study, women treated with Femhrt experienced a relief in the frequency and severity of their hot flashes.

      Osteoporosis Prevention: Femhrt has been shown to increase bone density when given in combination with calcium.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Femhrt exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Hot Flashes: You may notice an improvement in your symptoms after you start taking Femhrt.

      Osteoporosis Prevention: Your healthcare provider may order tests regularly to check your bone density.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Do not take Femhrt to prevent heart disease, heart attacks, strokes, or dementia (an illness involving confusion, loss of memory, and impaired judgment). Taking Femhrt may increase your chance of a heart attack, stroke, breast cancer, blood clots, or dementia.

      More common side effects may include: headache, breast pain, abdominal (stomach area) pain, fluid retention.

      Less common side effects may include:

      Vision problems, with symptoms such as double vision, bulging eyes, new severe headaches, or vision loss.

      Severely high blood calcium levels in women with breast cancer that has spread to the bones.

      Femhrt may also cause gallbladder or thyroid problems, increased blood pressure, or increased triglyceride (type of fat in the blood) levels.

    • Who should not take this medication?

      Do not take Femhrt if you are allergic to it or any of its ingredients.

      Do not take Femhrt if you have had your uterus removed (hysterectomy).

      Do not take Femhrt if you have unusual vaginal bleeding.

      Do not take Femhrt if you currently have or have had blood clots, liver problems, or certain cancers.

      Do not take Femhrt if you had a stroke or heart attack.

      Do not take Femhrt if you have been diagnosed with a bleeding disorder.

      Do not take Femhrt if you are pregnant or think you may be pregnant.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Femhrt. Also, talk to your healthcare provider about your complete medical history, especially if you have asthma; seizures; diabetes; migraines; endometriosis (a common gynecological disorder that may result in sores and pain); porphyria (a blood disorder); lupus (a disease that affects the immune system); heart, liver, thyroid, or kidney problems; high or low blood calcium levels; if you are scheduled for surgery or will be on bed rest; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Women: The recommended dose is one tablet once a day.

    • How should I take this medication?

      Take Femhrt exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Femhrt without first talking to your healthcare provider.

      You and your healthcare provider should talk regularly (every 3 to 6 months) about the dose you are taking and whether you still need treatment with Femhrt.

    • What should I avoid while taking this medication?

      Do not drink graprefruit juice while you are taking Femhrt.

    • What are the possible food and drug interactions associated with this medication?

      If Femhrt is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Femhrt may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Do not take Femhrt if you are pregnant. Femhrt can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Femhrt, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.