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  • Generic Name: (oxybutynin chloride)
    Other Brands: Gelnique
  • Last Revised: 07/2015
    • What is this medication and its most common uses?

      Gelnique 10% is a topical medicine (applied directly on the skin) used to treat overactive bladder and its symptoms, such as urinary urgency (a strong need to urinate right away), incontinence (a strong need to urinate with leaking or wetting accidents), or frequency (urinating often). Gelnique 10% is available as a gel.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Gelnique 10% works by interacting with natural body chemicals to relax the muscles in your bladder, thereby improving your symptoms.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Gelnique 10% has been shown to decrease the number of urinations per day.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use Gelnique 10% exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may notice an improvement in your urinary symptoms after you start using Gelnique 10%. Your healthcare provider may ask you a series of questions from time to time that will help assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: dry mouth; urinary tract infection; redness, rash, itching, pain at application site.

      Less common side effects may include:

      Serious allergic reactions, with symptoms such as hives; rash; itching; trouble breathing; or swelling of your face, mouth, or tongue.

      Central nervous system (the brain and spinal cord) effects, with symptoms such as headache, dizziness, and drowsiness.

      Fever and heat stroke due to decreased sweating may occur in high temperatures.

    • Who should not take this medication?

      Do not use Gelnique 10% if you are allergic to it or any of its ingredients.

      Do not use Gelnique 10% if you are not able to empty your bladder or have delayed or slow emptying of your stomach.

      Do not use Gelnique 10% if you have an eye problem called narrow-angle glaucoma (high pressure in your eye).

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Gelnique 10%. Also, talk to your healthcare provider about your complete medical history, especially if you have problems emptying your bladder completely, stomach problems, constipation, ulcerative colitis (an inflammatory disease of the large intestine), gastric reflux disease (a condition in which the stomach contents leak backwards from the stomach into the esophagus), esophagitis (inflammation of the tube between your mouth and stomach), or myasthenia gravis (a disease characterized by long-lasting fatigue and muscle weakness).

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Apply one packet once a day to the stomach, upper arms, shoulders, or thighs.

    • How should I take this medication?

      Use Gelnique 10% exactly as prescribed by your healthcare provider. Do not use more often or stop using Gelnique 10% without first talking to your healthcare provider.

      Apply Gelnique 10% only to dry, intact skin on your stomach, upper arms, shoulders, or thighs. Do not apply on open sores, recently shaved skin, or skin with rashes.

      Rotate your application site every day. Do not use the same site 2 days in a row. Changing application sites may reduce your chance of getting skin irritation.

      Wash your hands with soap and water immediately after applying Gelnique 10%.

      Cover the application site with clothing if skin-to-skin contact between another person and the application site is expected.

      Please review the instructions that came with your prescription on how to properly use Gelnique 10%.

    • What should I avoid while taking this medication?

      Do not drive, operate heavy machinery, or engage in other dangerous activities until you know how Gelnique 10% affects you.

      Do not take a bath, swim, shower, exercise, or get the application site wet for at least 1 hour after applying Gelnique 10%.

      Do not apply Gelnique 10% near fire, flames, or while smoking.

    • What are the possible food and drug interactions associated with this medication?

      If Gelnique 10% is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Gelnique 10% with the following: alcohol, certain medicines used to treat osteoporosis (such as alendronate), or medications known as anticholinergics (such as benztropine or dicyclomine).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Gelnique 10% during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Gelnique 10%, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

    • How should I store this medication?

      Store at room temperature in a dry place. Protect from moisture and humidity.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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