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  • Generic Name: (somatropin (rDNA origin))
    Other Brands: N/A
  • Last Revised: 10/2016
    • What is this medication and its most common uses?

      Genotropin is a medicine that contains human growth hormone and is used to treat growth failure in children who have low or no growth hormone. Genotropin is also used to treat children who have growth failure associated with certain conditions such as Prader-Willi syndrome (a genetic disorder that affects muscle tone), Turner syndrome (a genetic disorder that affects development in girls), and short stature or growth failure in children with idiopathic short stature (ISS). In addition, Genotropin is also used to treat adults who have low growth hormone levels. Genotropin is administered subcutaneously (just below the skin).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Growth hormone deficiency occurs when the pituitary gland does not produce enough growth hormone, resulting in a slower growth rate. Genotropin contains human growth hormone and works in the same way as growth hormone made by your body, thereby promoting growth.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Genotropin has been shown to increase the rate of growth in children. Genotropin has also been shown to increase lean body mass and decrease body fat in adults.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use Genotropin exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may measure your height regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: injection-site reactions, rashes, lipoatrophy (loss of fat tissue), headache.

      Less common side effects may include:

      Increased pressure within your skull with symptoms such as swelling in your eyes, changes in your vision, headache, nausea, vomiting.

      Increased risk of ear or hearing disorders and heart problems in people with Turner Syndrome.

      Genotropin may also cause pancreatitis (inflammation of your pancreas) and swelling.

    • Who should not take this medication?

      Do not use Genotropin if you are allergic to it or any of its ingredients.

      Do not use Genotropin if you are having serious complications after undergoing open heart surgery, abdominal (stomach area) surgery, serious injuries, or life-threatening breathing problems.

      Do not use Genotropin in children with Prader-Willi syndrome who are severely obese or have a history of breathing problems.

      Do not use Genotropin if you have cancer.

      Do not use Genotropin in children whose growth plates in their bones have closed.

      Do not use Genotropin if you have diabetes-related eye problems.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter and herbal medications you are taking before beginning treatment with Genotropin. Also, talk to your healthcare provider about your complete medical history, especially if you have heart problems, cancer, tumor(s), diabetes, pancreatitis, thyroid or pituitary problems, scoliosis (curvature of the spine), or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults and children: Your healthcare provider will prescribe the appropriate dose for you and your child, based on the condition and body weight.

    • How should I take this medication?

      Use Genotropin exactly as prescribed by your healthcare provider. Do not use it more often or stop using it without first talking to your healthcare provider.

      Your healthcare provider will give you instructions on how to prepare and inject Genotropin.

      Inject Genotropin in your abdomen, thighs, or buttocks. Rotate the injection sites.

    • What should I avoid while taking this medication?

      Do not use Genotropin if the solution is cloudy or has particles in it after mixing.

      Do not use Genotropin until your healthcare provider shows you how to use it correctly.

      Do not miss any scheduled follow-up appointments with your healthcare provider.

      Do not shake Genotropin.

    • What are the possible food and drug interactions associated with this medication?

      If Genotropin is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Genotropin with the following: corticosteroids (such as cortisone or prednisone), cyclosporine, estrogen, insulin, or seizure medications (such as carbamazepine or phenytoin).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Genotropin during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Genotropin, use it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not use two doses at once.

    • How should I store this medication?

      Store in the refrigerator. Do not freeze. Protect from light.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
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