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  • Generic Name: (propranolol hydrochloride)
    Other Brands: N/A
  • Last Revised: 01/2015
    • What is this medication and its most common uses?

      Hemangeol is a medicine used to treat a condition called proliferating infantile hemangioma (sometimes called "strawberry marks").

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Hemangeol is thought to work directly on the blood vessels that make up the hemangioma. It narrows the blood vessels that already formed, prevents new ones from growing, and destroys and removes these unwanted cells from inside the hemangioma. 

      What are the beneficial effects of this medication and when should I begin to have results?

      What: In a clinical trial, 60% of babies receiving Hemangeol had their hemangioma lesion completely or nearly completely resolved by 6 months of therapy versus only 4% of babies given no treatment.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider’s directions. It is important that you give Hemangeol to your child exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your child's hemangioma should begin to get smaller after starting treatment with Hemangeol.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: sleep problems, worsening respiratory tract infections, diarrhea, vomiting.

      Less common side effects may include:

      Low blood sugar, with signs or symptoms such as paleness, blue or purple skin color, sweating, irritability, crying for no apparent reason, irregular or fast heartbeat, poor feeding, low body temperature, unusual sleepiness, seizures, breathing stops for short periods of time, and loss of consciousness.

      New or worsening slow heart rate or low blood pressure, with symptoms such as pale skin color, slow or uneven heartbeats, cold arms or legs, blue or purple skin color, or fainting.

      Increased risk of stroke in certain children who have severe problems with the blood vessels in their brain, particularly if your child has a large hemangioma that affects the face or head.

      Hemangeol may also cause breathing problems or wheezing.

    • Who should not take this medication?

      Do not give Hemangeol to your child if he/she is allergic to it or any of its ingredients.

      Do not give Hemangeol to your child if he/she was born prematurely and has not reached the corrected age of 5 weeks.

      Do not give Hemangeol to your child if he/she weighs less than 4 1/2 pounds.

      Do not give Hemangeol to your child if he/she has asthma or a history of breathing problems.

      Do not give Hemangeol to your child if he/she has a heart problem, slow heart rate (<80 beats per minute), or very low blood pressure.

      Do not give Hemangeol to your child if he/she has pheochromocytoma (a tumor on the adrenal gland).

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your child's healthcare provider about all prescription, over-the-counter, and herbal medications your child is taking before beginning treatment with Hemangeol. Also, talk to your healthcare provider about your child's complete medical history, especially if your child has a lower respiratory tract infection.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Infants 5 weeks-1 year: Your healthcare provider will prescribe the appropriate dose for your child based on his/her weight. Your healthcare provider may adjust the dose as your child’s weight changes.

    • How should I take this medication?

      Give Hemangeol to your child exactly as your healthcare provider tells you. Do not change the dose or stop giving Hemangeol to your child without first talking to your child's healthcare provider.

      Always give Hemangeol during or immediately after a feeding. Hemangeol is given 2 times each day, at least 9 hours apart.

      If your child refuses to take Hemangeol through the oral dosing syringe, it can be mixed with a small amount of fruit juice or milk (breast or formula). Do not mix Hemangeol with a full bottle of milk or fruit juice.

      If your child spits up a dose or if you are not sure your child got all of the medicine, do not give another dose. Wait until the next scheduled dose.

      Please review the instructions that came with your child's prescription for information about the correct way to prepare and give a dose of Hemangeol.

    • What should I avoid while taking this medication?

      Do not give Hemangeol to your child if he/she is not eating, for example, due to an illness or vomiting, until feedings are normal again.

    • What are the possible food and drug interactions associated with this medication?

      If Hemangeol is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Hemangeol may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications your child is taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Hemangeol is not for use in pregnant or breastfeeding women.

    • What should I do if I miss a dose of this medication?

      If your baby has missed a dose of Hemangeol or you are unsure whether they have gotten the entire dose due to vomiting, you can wait until the next scheduled dose. There is no need to make up the missed dose.

    • How should I store this medication?

      Store at room temperature. Do not freeze. Do not shake before use.

      Safely throw away any opened bottle after 2 months, even if there is medicine left in the bottle.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
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