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  • Generic Name: (palbociclib)
    Other Brands: N/A
  • Last Revised: 03/2016
    • What is this medication and its most common uses?

      Ibrance is a medicine used in combination with another medicine to treat certain types of breast cancer.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Ibrance works by slowing down the growth and spread of tumors.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By slowing down the growth and spread of tumors, Ibrance may help to improve your condition.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Ibrance exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: low red or white blood cell counts, tiredness, infections, upper respiratory infection, nausea, mouth sores, hair loss, diarrhea, headache, low platelet (a type of blood cell that forms clots to help stop bleeding) counts, decreased appetite, vomiting, rash.

      Less common side effects may include:

      Blood clots in the arteries of your lungs, with symptoms such as shortness of breath; sudden, sharp chest pain that may become worse with deep breathing; rapid heart rate; or rapid breathing.

      Harm to your unborn baby. Tell your healthcare provider immediately if you are pregnant or plan to become pregnant.

    • Who should not take this medication?

      Do not take Ibrance if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Ibrance. Also, talk to your healthcare provider about your complete medical history, especially if you have liver or kidney problems; fever, chills, or any other signs or symptoms of infection; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Women: The recommended dose is a 125-milligram capsule once a day for 21 straight days, followed by 7 days with no treatment.

      Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

      If you are taking certain other medicines, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Take Ibrance exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Ibrance without first talking to your healthcare provider.

      Take Ibrance with food, at approximately the same time each day.

      Swallow Ibrance whole. Do not chew, crush, or open the capsules.

      It is important that women who may become pregnant use effective birth control during treatment and for at least 3 weeks after the last dose. Also, men with female partners who may become pregnant should use effective birth control during treatment and for 3 months after the last dose. Talk to your healthcare provider about appropriate birth control.

      If you vomit after taking your dose, do not take an additional dose.

    • What should I avoid while taking this medication?

      Do not eat grapefruit or drink grapefruit juice during treatment with Ibrance.

    • What are the possible food and drug interactions associated with this medication?

      If Ibrance is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Ibrance may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Ibrance can harm your unborn baby if you take it during pregnancy. The effects of Ibrance during breastfeeding are unknown. Do not breastfeed while you are taking Ibrance and for 3 weeks after the last dose. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Ibrance, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.