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  • Generic Name: (talimogene laherparepvec)
    Other Brands: N/A
  • Last Revised: 12/2015
    • What is this medication and its most common uses?

      Imlygic is a medicine used to treat a type of cancer called melanoma when it is on your skin or in your lymph glands. Your healthcare provider will inject Imlygic directly into your tumor.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Imlygic is a weakened form of the herpes simplex virus type 1, which is commonly called the cold sore virus. Imlygic is thought to reproduce inside cancer cells and is designed to kill those cells.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By killing cancer cells, Imlygic may help improve your condition.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions.

      How do I know it is working?

      Your healthcare provider may ask you questions from time to time to assess how well this medicine is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: tiredness, chills, fever, nausea, flu-like symptoms, injection-site pain.

      Less common side effects may include:

      Imlygic may cause herpes infections (including cold sores and herpetic keratitis).

    • Who should not take this medication?

      Your healthcare provider will not administer Imlygic to you if you are allergic to it or any of its ingredients.

      Your healthcare provider will not administer Imlygic to you if you are pregnant.

      Your healthcare provider will not administer Imlygic to you if you have a weakened immune system.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Imlygic. Also, talk to your healthcare provider about your complete medical history, especially if you have or ever had an HIV infection or AIDS, blood or bone marrow cancer, autoimmune disease, or other medical conditions that can weaken your immune system; if you are taking steroids or other medicines that suppress your immune system; if you are taking antiviral medicines to help treat or prevent herpes; if you have been in close contact with someone who has a weakened immune system or is pregnant; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you.

    • How should I take this medication?

      Your healthcare provider will administer Imlygic to you.

      Keep the injection site covered for at least the first week after each treatment visit or longer if the injection site is weeping or oozing. Replace the dressing if it falls off.

      Wear gloves while putting on or changing your dressings.

      Throw away used dressings and cleaning materials in household waste in a sealed plastic bag.

      It is important that women who may become pregnant use an effective birth control during treatment with Imlygic. Talk to your healthcare provider about appropriate birth control options.

    • What should I avoid while taking this medication?

      Do not touch or scratch the treatment site.

      Do not allow direct contact between your treatment sites, dressings, or body fluids and close contacts (such as household members, caregivers, or persons sharing the same bed). If accidental exposure occurs, clean the exposed area with soap and water and/or a disinfectant. Contact your healthcare provider if symptoms of herpetic infection develop.

    • What are the possible food and drug interactions associated with this medication?

      If Imlygic is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Imlygic with acyclovir or other herpes medicines.

    • May I receive this medication if I am pregnant or breastfeeding?

      Imlygic may harm your unborn baby. The effects of Imlygic during breastfeeding are unknown. Do not breastfeed while you are receiving Imlygic. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      Imlygic should be given under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider for advice.

    • How should I store this medication?

      Your healthcare provider will store this medication for you.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.