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  • Generic Name: (empagliflozin)
    Other Brands: N/A
  • Last Revised: 08/2016
    • What is this medication and its most common uses?

      Jardiance is a medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Jardiance works with your kidneys to help remove sugar through the urine.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: In a clinical study, Jardiance helped some people achieve a hemoglobin A1C (measures your average blood sugar levels over a 2- to 3-month period) of less than 7%.

      When: In clinical studies, some patients experienced lower hemoglobin A1C numbers 24 weeks into their treatment. However, everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Jardiance exactly as your healthcare provider prescribed.

      How do I know it is working?

      Check your blood sugar as instructed by your healthcare provider. Your healthcare provider may also do regular blood tests to measure your blood sugar levels and your hemoglobin A1C. Stay on your prescribed diet and exercise program, as this may also affect the results of your blood tests.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: urinary tract infections, vaginal yeast infections.

      Symptoms of a vaginal yeast infection may include: vaginal odor, white or yellowish vaginal discharge (may be lumpy or look like cottage cheese), or vaginal itching.

      Less common side effects may include:

      Dehydration (loss of body water and salt), with symptoms such as dizziness, lightheadedness, or weakness, especially when you stand up. Talk to your healthcare provider about what you can do to prevent dehydration, including how much fluid you should drink on a daily basis.

      Ketoacidosis (increased ketones in your blood or urine), with symptoms such as nausea, tiredness, vomiting, trouble breathing, or abdominal (stomach area) pain. Ketoacidosis can happen even if your blood sugar is less than 250 mg/dL.

      Serious urinary tract infections, with symptoms such as a burning feeling when passing urine, a need to urinate often, the need to urinate right away, pain in the lower part of your stomach (pelvis), or blood in your urine. Sometimes people also may have a fever, back pain, nausea, or vomiting.

      If you take Jardiance with another medicine that can cause low blood sugar, such as insulin or sulfonylureas (such as glimepiride, glipizide, or glyburide), your risk of getting low blood sugar is higher. Symptoms of low blood sugar may include headache, weakness, confusion, shaking, feeling jittery, drowsiness, dizziness, irritability, sweating, fast heartbeat, or hunger.

      Yeast infection of the penis. Certain men who are not circumcised may have swelling of the penis that makes it difficult to pull back the skin around the tip of the penis. Other symptoms include redness, itching, or swelling of the penis; rash of the penis; foul smelling discharge from the penis; or pain in the skin around the penis.

      Jardiance may also cause kidney problems (especially in people 75 years of age or older and people who already have kidney problems) or increase fats in your blood called LDL cholesterol (bad cholesterol).

    • Who should not take this medication?

      Do not take Jardiance if you are allergic to it or any of its ingredients.

      Do not take Jardiance if you have severe kidney problems or are on dialysis.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Jardiance. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems; have a history of urinary tract infections or problems urinating; have or have had problems with your pancreas (including pancreatitis or surgery on your pancreas); drink alcohol very often or drink a lot of alcohol in a short period of time ("binge" drink); are going to have surgery; are eating less due to illness, surgery, or a change in your diet; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 10 milligrams once a day, in the morning. Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

      If you are also using insulin or taking another diabetes medicine called a sulfonylurea, your healthcare provider may adjust the dose of these medicines.

      If your body is under some types of stress such as a fever, infection, trauma (such as a car accident), or surgery, your healthcare provider may need to adjust your diabetes medicine.

    • How should I take this medication?

      Take Jardiance exactly as prescribed by your healthcare provider.

      Take Jardiance with or without food.

      Stay on your prescribed diet and exercise program while taking Jardiance.

      When taking Jardiance, you may have sugar in your urine, which will show up on a urine test.

    • What should I avoid while taking this medication?

      Do not change your dose or stop taking Jardiance without first talking to your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Jardiance is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Jardiance with the following: insulin or certain other medicines that can lower your blood sugar, and water pills.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Jardiance during pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking Jardiance. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Jardiance, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.