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Laviv is a personalized cell therapy that uses your own fibroblasts (skin cells that produce collagen) to improve the appearance of wrinkles that go from the sides of your nose to the corners of your mouth. Laviv is injected into your face.
How does this medication work?
Laviv is thought to work by replenishing collagen to your skin. Collagen provides firmness and structure to your skin and is essential in supporting the middle layer of your skin.
What are the beneficial effects of this medication and when should I begin to have results?
What: In clinical trials, people treated with Laviv had significantly improved appearances of smile lines than people who were not treated with Laviv.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider’s directions. The effects of Laviv may be seen over the course of the three-treatment regimen.
How do I know it is working?
You may notice an improvement in your smile lines after you start receiving Laviv.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: injection-site reactions such as redness, bruising, swelling, pain, bleeding, lumps, irritation, itchiness.
Less common side effects may include:
Serious allergic reactions, with symptoms such as itching, rash, red and itchy welts, wheezing, asthma symptoms, dizziness, or feeling faint.
Laviv may also cause cold sores on your mouth.
Your healthcare provider will not administer Laviv to you if you are allergic to it, any of its ingredients, to certain medications (such as gentamicin, amphotericin, or dimethyl sulfoxide), or to cattle products.
Your healthcare provider will not administer Laviv to you if you have an infection at the site to be injected.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Laviv. Also, talk to your healthcare provider about your complete medical history, especially if you have allergic reactions to any drugs or food, bleeding disorders, excessive scarring on your face, skin cancer, genetic disorders affecting your skin, or immune problems or take medicines that affect your immune system.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: Your healthcare provider will prescribe and administer the appropriate dose for you.
Before you start your Laviv therapy, your healthcare provider will take three small skin samples from behind your ears and send them to the manufacturer, where certain cells called fibroblasts will be grown from the samples. After 3-6 months, the samples are sent back to your healthcare provider who will inject them into your face.
You will receive Laviv in three treatment sessions about 3-6 weeks apart.
Do not apply ice to your face after receiving Laviv.
Do not wash the site of injection for at least 24 hours after receiving Laviv.
Do not scrub, rub, manipulate, or apply any products (such as makeup, face creams, or sunscreen) to the treatment area for 72 hours after receiving Laviv.
Do not take blood thinners (such as warfarin) or aspirin while you are receiving Laviv.
Do not miss any follow-up appointments with your healthcare provider. If you need to miss an appointment, notify your healthcare provider no later than 2 days prior to your scheduled appointment to reschedule.
No significant interactions have been reported with Laviv at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.
Laviv should be given under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider or pharmacist for advice.
Your healthcare provider will store this medication for you.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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