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  • Generic Name: (methylphenidate hydrochloride)
    Other Brands: N/A
  • Last Revised: 07/2014
    • What is this medication and its most common uses?

      Metadate ER is a medicine used to treat attention-deficit hyperactivity disorder (ADHD). Metadate ER is also used to treat a condition known as narcolepsy (a sleep disorder characterized by excessive daytime sleepiness).

      Metadate ER is a federally controlled substance because it has abuse potential.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Metadate ER is an extended-release medicine (a type of tablet that releases medicine into your body throughout the day). Metadate ER works by changing the amount of certain chemicals in your brain, thereby improving symptoms of ADHD and narcolepsy.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Metadate ER is an important part of a total treatment program for people with ADHD that may include counseling or other therapies. Metadate ER may help increase attention and decrease impulsiveness and hyperactivity in people with ADHD.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Metadate ER exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may start to notice an improvement in your symptoms. This is a good indicator that your medication is working. Your healthcare provider may ask you questions from time to time to assess how well your medicine is working and to check for improvement of your condition.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Metadate ER is a federally controlled substance because it can be abused or lead to dependence. Keep Metadate ER in a safe place to prevent misuse and abuse. Selling or giving away Metadate ER may harm others, and is against the law.

      More common side effects may include: nervousness, sleeplessness.

      Less common side effects may include:

      Sudden death in people who have heart problems or heart defects; stroke and heart attack in adults; increased blood pressure and heart rate with symptoms such as chest pain, shortness of breath, or fainting.

      Mental problems with symptoms such as new or worsening behavior and thought problems, bipolar illness, aggressive behavior, or hostility. Children and teenagers may also begin to hear voices, believe in things that are not true, or become suspicious.

      Slowing of growth (height and weight) in children.

      Seizures, mainly in people with a history of seizures.

      Eyesight changes or blurred vision.

      Prolonged and painful erections.

      Circulation problems in your fingers and toes with symptoms such as feeling numb, cool, or painful, or changing color (such as from pale to blue to red).

    • Who should not take this medication?

      Do not take Metadate ER if you are allergic to it or any of its ingredients.

      Do not take Metadate ER if you are very anxious, tense, or agitated.

      Do not take Metadate ER if you have glaucoma (high pressure in the eye), tics (repeated movements or sounds that cannot be controlled), Tourette's syndrome (a brain disorder characterized by tics), or a family history of Tourette's syndrome.

      Do not take Metadate ER if you have high blood pressure, heart problems, or hyperthyroidism (an overactive thyroid gland).

      Do not take Metadate ER if you are taking an antidepressant medication called a monoamine oxidase inhibitor (MAOI) (such as phenelzine or selegiline) or have taken any within the past 14 days.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Metadate ER. Also, talk to your healthcare provider about your complete medical history, especially if you have heart problems, heart defects, high blood pressure, mental problems (such as psychosis, mania, bipolar disorder, or depression), or a family history of these problems; tics or Tourette's syndrome; seizures; or if you have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults and children ≥6 years: Your healthcare provider will prescribe the appropriate dose for you based on your previous ADHD medication.

    • How should I take this medication?

      Take Metadate ER exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Metadate ER without first talking to your healthcare provider.

      Swallow Metadate ER tablets whole with water or other liquids. Do not crush or chew the tablets.

    • What should I avoid while taking this medication?

      Do not drive or operate dangerous machinery until you know how Metadate ER affects you.

      Do not start any new medicines while taking Metadate ER without first talking to your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Metadate ER is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Metadate ER with any of the following: blood pressure medicines, blood thinners (such as warfarin), certain antidepressants known as tricyclic antidepressants (such as imipramine, clomipramine, or desipramine), or seizure medications (such as phenobarbital or phenytoin).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Metadate ER during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Metadate ER, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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