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Mozobil is a medicine used in combination with granulocyte-colony stimulating factor (G-CSF) (substances that stimulate growth) to move stem cells into the bloodstream for collection and autologous transplantation (stem cell transplant using your own stem cells) in people with non-Hodgkin's lymphoma and multiple myeloma. Mozobil is administered subcutaneously (injected just below the skin).
How does this medication work?
Mozobil works by stimulating stem cells to move out of the bone marrow and into the bloodstream for collection.
What are the beneficial effects of this medication and when should I begin to have results?
What: In clinical studies, people using Mozobil with G-CSF had several benefits compared to those using G-CSF alone. People receiving Mozobil in combination with G-CSF had more stem cells collected per session, fewer sessions needed, and more people were able to proceed to autologous transplant and had successful regrowth of stem cells.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions.
How do I know it is working?
Your healthcare provider will monitor you regularly to assess how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: diarrhea, nausea, tiredness, injection site reaction (itching or rash), headache, pain in your joints, dizziness, vomiting.
Less common side effects may include:
Serious allergic reactions with symptoms such as a hives, swelling around your eye(s), or difficulty breathing.
Enlarged spleen with symptoms such as pain in the left upper stomach area or left shoulder area.
Increased white blood cell counts or thrombocytopenia (a decrease in the number of platelets [a type of blood cells that form clots to help stop bleeding] circulating in the blood).
Harm to your unborn baby if used during pregnancy. Tell your healthcare provider right away if you are pregnant or plan to become pregnant.
Mozobil may also cause cancer cells to be released from the bone marrow and collected along with your stem cells.
Your healthcare provider will not administer Mozobil to you if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Mozobil. Also, talk to your healthcare provider about your complete medical history, especially if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your condition and body weight.
Your healthcare provider will administer Mozobil for you.
It is important that you use effective contraception while you are receiving Mozobil. Talk to your healthcare provider regarding appropriate birth control.
Do not miss any scheduled follow-up appointments with your healthcare provider.
Do not become pregnant while you are receiving Mozobil.
No significant interactions have been reported with Mozobil at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.
Mozobil may harm your unborn baby if you receive it during pregnancy. Do not breastfeed while you are receiving Mozobil. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
Mozobil should be given under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider for advice.
Your healthcare provider will store this medication for you.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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