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  • Generic Name: (dronedarone)
    Other Brands: N/A
  • Last Revised: 07/2014
    • What is this medication and its most common uses?

      Multaq is a medicine used to lower the chance of going into the hospital due to atrial fibrillation (an irregular, fast heartbeat) in people who have had certain types of atrial fibrillation in the past, but now have normal heart rhythm.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      It is unknown exactly how Multaq works to help your heart beat more regularly.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Multaq has been shown to reduce the rate of hospitalization due to atrial fibrillation

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Multaq exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Multaq should not be used if you have symptoms of heart failure that recently worsened and required hospitalization, or if you have an irregular heart rhythm called permanent atrial fibrillation, due to increased risk for developing a life-threatening stroke or heart failure. Call your healthcare provider right away if you develop symptoms such as shortness of breath or wheezing at rest; chest tightness; coughing up frothy mucus at rest, night time, or after minor exercise; needing to use more pillows to prop yourself up at night to breathe easily; gaining more than 5 pounds quickly; or increased swelling of your feet or legs.

      More common side effects may include: diarrhea, nausea, stomach area pain, vomiting, weakness, tiredness, indigestion, skin problems (such as redness, rash, and itching).

      Less common side effects may include:

      Liver problems, including life-threatening liver failure, with symptoms such as loss of appetite, nausea, and vomiting; fever, feeling unwell, and unusual tiredness; itching; yellowing of the skin or the whites of the eyes; unusual darkening of the urine; or right upper stomach area pain or discomfort.

      Life-threatening lung damage, with symptoms such as shortness of breath, wheezing, or any other trouble breathing; or coughing, chest pain, or spitting up blood.

      Lowered potassium or magnesium levels in your blood.

      Harm to your baby if taken during pregnancy. Tell your healthcare provider right away if you become pregnant while taking Multaq.


    • Who should not take this medication?

      Do not take Multaq if you are allergic to it or any of its ingredients.

      Do not take Multaq if you have a type of irregular heart rhythm called permanent atrial fibrillation.

      Do not take Multaq if you have symptoms of heart failure that recently worsened and you were hospitalized, or if you have severe heart failure.

      Do not take Multaq if you are currently taking any of the following medications: certain anti-psychotics (such as chlorpromazine), antidepressant medications (such as amitriptyline), certain antibiotics (such as erythromycin), certain heart medications (such as metoprolol or amiodarone), ketoconazole, itraconazole, voriconazole, cyclosporine, telithromycin, clarithromycin, nefazodone, or ritonavir.

      Do not take Multaq if you have serious liver problems or have a history of liver or lung damage after taking a medicine called amiodarone.

      Do not take Multaq if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Multaq. Also, talk to your healthcare provider about your complete medical history, especially if you have other heart problems, liver or kidney problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 400 mg twice a day.

    • How should I take this medication?

      Take Multaq exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Multaq without first talking to your healthcare provider.

      Take Multaq twice a day with food, once with your morning meal and once with your evening meal.

    • What should I avoid while taking this medication?

      Do not drink grapefruit juice while you are taking Multaq.

    • What are the possible food and drug interactions associated with this medication?

      If Multaq is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Multaq may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      Multaq can harm your baby if you take it during pregnancy. Do not breastfeed while you are taking Multaq. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Multaq, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.