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Myfortic is a medicine used in combination with other medicines to help prevent organ rejection in people who have had a kidney transplant. Myfortic is a delayed-release medicine (releases medicine into your body at a later time from when you take it).
How does this medication work?
Your immune system is your body's defense against things that can cause infection and disease. Unfortunately, it cannot tell the difference between a harmful virus or bacteria and your new organ, so its natural response is to reject it. Myfortic works by stopping your immune system from rejecting your new organ.
What are the beneficial effects of this medication and when should I begin to have results?
What: Myfortic may reduce the incidence of organ rejection following transplantation.
When: Though you may not feel a change in the way you feel, it is very important to keep taking your medicine as prescribed to prevent your body from rejecting your new organ.
How do I know it is working?
Your healthcare provider may order tests regularly to check the amount of Myfortic in your body and may ask you questions from time to time to assess how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Myfortic can increase your risk of loss of a pregnancy (miscarriage), especially during the first 3 months of pregnancy, and can increase the risk of birth defects. Talk to your healthcare provider about using appropriate birth control methods during treatment with Myfortic and for 6 weeks after stopping Myfortic. You should have one pregnancy test immediately before starting Myfortic, and another pregnancy test 8 to 10 days later. Pregnancy tests may be repeated during routine follow-up visits with your healthcare provider. Discuss the results of your pregnancy test with your healthcare provider.
Myfortic can increase your risk of developing lymphoma (a type of cancer involving cells of the immune system, called lymphocytes) and other types of cancers (including skin cancer).
Myfortic can also increase your risk of developing infections. Tell your healthcare provider immediately if you have symptoms of an infection such as a fever; cold symptoms, such as a runny nose or sore throat; flu symptoms, such as an upset stomach, stomach pain, vomiting, or diarrhea; earache or headache; pain during urination or if you need to urinate often; white patches in the mouth or throat; unexpected bruising or bleeding; or cuts, scrapes, or incisions that are red, warm, and oozing pus.
Your Myfortic therapy is managed in a hospital or medical facility under the supervision of your healthcare provider who is experienced in administering this medicine.
Common side effects may include: anemia (low red blood cell counts), leukopenia (low white blood cell counts), constipation, nausea, diarrhea, vomiting, upset stomach, urinary tract infection, cytomegalovirus infection (certain viral infection), trouble sleeping, pain after surgery.
Less common side effects may include:
Stomach problems with symptoms such as bleeding in the stomach and intestines or sudden onset or persistent abdominal (stomach area) pain.
Do not take Myfortic if you are allergic to it, any of its ingredients, or to a similar medicine called mycophenolate mofetil.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Myfortic. Also, talk to your healthcare provider about your complete medical history, especially if you have digestive problems (such as ulcers), a rare inherited disorder (such as Lesch-Nyhan or Kelley-Seegmiller syndrome), if you plan to receive any live vaccines, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended dose is 720 milligrams twice a day.
Children ≥5 years (at least 6 months post-transplant): Your healthcare provider will prescribe the appropriate dose for your child, based on his/her height and weight.
Take Myfortic exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Myfortic without first talking to your healthcare provider.
Take Myfortic on an empty stomach (1 hour before or 2 hours after food).
Do not crush, chew, or cut Myfortic tablets before taking them. Swallow Myfortic tablets whole.
Do not change (substitute) between using Myfortic tablets and mycophenolate mofetil tablets, capsules, or oral suspension for one another unless your healthcare provider tells you to. These medicines are absorbed differently, and this may affect the amount of medicine in your blood.
Women must use acceptable birth control during Myfortic therapy and for 6 weeks after stopping Myfortic, unless at any time you choose to avoid sexual intercourse (abstinence) with a man completely. Talk to your healthcare provider about birth control methods that can be used while taking Myfortic.
Do not become pregnant while you are taking Myfortic.
Do not expose yourself to sunlight and ultraviolet light, such as tanning beds or sunlamps, wear protective clothing, and use sunscreen with a high sun protection factor (SPF 30 and above).
Do not receive any live vaccines (such as flu vaccine through your nose, or measles, mumps, rubella, tuberculosis, yellow fever, chickenpox, or typhoid vaccines) while taking Myfortic.
If Myfortic is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Myfortic with the following: acyclovir, antacids that contain aluminum or magnesium, azathioprine, birth control pills, cholestyramine, ganciclovir, metronidazole and norfloxacin combination, rifampin, valacyclovir, valganciclovir, or sevelamer.
Myfortic can harm your unborn baby if you take it during pregnancy. Do not become pregnant while you are taking Myfortic. The effects of Myfortic during breastfeeding are unknown. Do not breastfeed while you are taking Myfortic. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you become pregnant while taking Myfortic, do not stop taking Myfortic. Call your healthcare provider right away. In certain situations, you and your healthcare provider may decide that taking Myfortic is more important to your health than the possible risks to your unborn baby. Talk to your healthcare provider about registering with the Mycophenolate Pregnancy Registry. The purpose of this registry is to collect information about the health of your baby.
If you miss a dose of Myfortic, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature. Protect from moisture.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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