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  • Generic Name: (rimabotulinumtoxinb)
    Other Brands: N/A
  • Last Revised: 05/2014
    • What is this medication and its most common uses?

      Myobloc is a medicine used to treat abnormal head position and neck pain associated with cervical dystonia (a movement disorder characterized by the pulling of the neck and shoulder muscles). Myobloc is available as an intramuscular (injected directly into the muscle) injection.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Myobloc works by reducing nerve stimulation to the injected muscles. This reduces muscle activity that is causing your symptoms.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: In clinical studies, Myobloc was shown to decrease neck pain.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions.

      How do I know it is working?

      You may notice an improvement in your symptoms after you start receiving Myobloc. Your healthcare provider may ask you a series of questions from time to time that will help assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      In some cases, the effects of Myobloc may reach areas of the body away from the injection site and cause symptoms of a serious condition called botulism. Contact your healthcare provider right away if you experience problems swallowing, speaking, or breathing; loss of strength and muscle weakness all over your body; double vision, blurred vision, or drooping eyelids; hoarseness or change or loss of your voice; trouble speaking clearly; or loss of your bladder control. These may be symptoms of botulism and can occur hours, days, or weeks after you receive an injection of Myobloc.

      More common side effects may include: dry mouth, difficulty swallowing, indigestion, injection site pain.

      Less common side effects may include:

      Serious allergic reactions, with symptoms such as itching, rash, red and itchy welts, wheezing, asthma symptoms, dizziness, or feeling faint.

    • Who should not take this medication?

      Your healthcare provider will not administer Myobloc to you if you are allergic to it, any of its ingredients, or to other similar medications (such as Botox, Dysport, or Xeomin).

      Your healthcare provider will not administer Myobloc to you if you have an infection at the site to be injected.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Myobloc. Also, talk to your healthcare provider about your complete medical history, especially if you have a disease that affects your muscles and nerves (such as Lou Gehrig's disease, myasthenia gravis [loss of muscular control], or Lambert-Eaton syndrome); breathing problems (such as asthma or emphysema); swallowing problems; bleeding problems; weakness of your forehead muscles (such as trouble raising your eyebrows); drooping eyelids; urinary tract infection; problems emptying your bladder; are scheduled for surgery; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your condition.

    • How should I take this medication?

      Your healthcare provider will administer Myobloc injection to you.

    • What should I avoid while taking this medication?

      Do not drive, operate heavy machinery, or engage in other dangerous activities until you know how Myobloc affects you.

      Do not miss any scheduled follow-up appointments with your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Myobloc is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Myobloc with the following: anticholinergics (such as diphenhydramine and oxybutynin), aspirin, blood thinners (such as warfarin), certain antibiotics (such as gentamicin and neomycin), muscle relaxants (such as carisoprodol and cyclobenzaprine), or other medications containing the similar ingredient as Myobloc (such as Botox, Dysport, and Xeomin).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Myobloc during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      Myobloc should be given under special circumstances determined by your healthcare provider. If you miss your scheduled dose, contact your healthcare provider or pharmacist for advice.

    • How should I store this medication?

      Your healthcare provider will store this medication for you.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.