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Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis and rheumatoid arthritis.
How does this medication work?
Nabumetone blocks a substance in your body that is involved in causing inflammation and pain in parts of the body where there is arthritis.
What are the beneficial effects of this medication and when should I begin to have results?
What: Nabumetone may relieve signs and symptoms of arthritis, such as pain, swelling, and stiffness.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take nabumetone exactly as your healthcare provider has prescribed.
How do I know it is working?
You may feel relief in your arthritis symptoms after you start taking nabumetone. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Nabumetone may increase the chance of a life-threatening heart attack or stroke. This risk may occur early in treatment and may increase with longer use. Call your healthcare provider right away if you develop chest pain, shortness of breath, weakness, or slurring of your speech while taking nabumetone.
Nabumetone should never be used right before or after a heart surgery called a coronary artery bypass graft (CABG).
Nabumetone may increase the risk of bleeding, ulcers, and tears (perforation) of the stomach or intestines. This can occur any time during treatment without warning symptoms, and may be life threatening. The chance of a person getting an ulcer or bleeding increases with longer use, smoking, drinking alcohol, older age, having poor health, and if you are taking certain medicines such as corticosteroids (such as prednisone) or blood thinners (such as warfarin). Call your healthcare provider right away if you develop stomach pain, indigestion, bloody or tarry stools, or you vomit blood while taking nabumetone.
More common side effects may include: diarrhea, upset stomach, stomach pain.
Less common side effects may include:
Liver problems with symptoms such as nausea, tiredness, weakness, itching, yellowing of your skin or the whites of your eyes, right upper stomach pain, and flu-like symptoms.
Serious allergic reactions with symptoms such as skin rash, blisters, fever, itching, trouble breathing, or swelling of your face or throat.
Nabumetone may cause high blood pressure, photosensitivity (increased sensitivity to sunlight), anemia (low red blood cell counts), kidney problems, or unexplained weight gain or swelling.
Do not take nabumetone if you are allergic to it or any of its ingredients.
Do not take nabumetone if you have had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID (such as ibuprofen or naproxen).
Do not take nabumetone right before or after a heart bypass surgery.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with nabumetone. Also, talk to your healthcare provider about your complete medical history, especially if you have asthma; high blood pressure or heart failure; kidney or liver problems; a history of ulcers or bleeding in your stomach or intestines; or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended starting dose is 1000 milligrams once a day. Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.
If you have kidney impairment, your healthcare provider may adjust your dose appropriately.
Take nabumetone exactly as prescribed by your healthcare provider. Do not change your dose without first talking to your healthcare provider.
Take nabumetone with or without food.
Do not take other NSAIDs in combination with nabumetone without first talking to your healthcare provider.
If nabumetone is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining nabumetone with the following: aspirin, blood pressure/heart medications known as angiotensin-converting enzyme (ACE) inhibitors (such as enalapril and lisinopril), lithium, methotrexate, warfarin, or water pills (such as furosemide or hydrochlorothiazide).
Do not take nabumetone during pregnancy (especially if you are in the late stage of your pregnancy). The effects of nabumetone during early pregnancy and breastfeeding are unknown. Do not breastfeed while you are taking nabumetone. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of nabumetone, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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