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  • Generic Name: (quinidine gluconate)
    Other Brands: N/A
  • Last Revised: 04/2015
    • What is this medication and its most common uses?

      Quinidine is a medicine used to restore normal heart rhythm in people with atrial fibrillation (an irregular, fast heartbeat) and to reduce the frequency of atrial fibrillation. Quinidine is also used to suppress ventricular arrhythmias (a certain type of life-threatening irregular heartbeat). Quinidine is an extended-release medicine (a type of tablet that releases medicine into your body throughout the day).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Quinidine works by changing the electrical activity of the heart, thereby regulating your heart rhythm.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Quinidine may help to make your heart beat more regularly.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take quinidine exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Quinidine may increase your risk of life-threatening effects.

      More common side effects may include: diarrhea, nausea, vomiting, heartburn.

      Less common side effects may include:

      New or worsened abnormal heartbeats that can be life-threatening.

      Quinidine may also cause low platelet (a type of blood cell that forms clots to help stop bleeding) counts.

    • Who should not take this medication?

      Do not take quinidine if you are allergic to it or any of its ingredients.

      Do not take quinidine if you previously developed thrombocytopenic purpura (a condition in which blood clots form in the blood vessels and can occur all over the body) to quinidine or to another medicine called quinine.

      Do not take quinidine if your heart rhythm depends on a certain type of pacemaker.

      Do not take quinidine if you previously experienced a side effect with medicines known as anticholinergics (such as ipratropium).

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with quinidine. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney, heart, or liver problems; congestive heart failure (a condition in which the heart cannot pump enough blood throughout the body); sick sinus syndrome (abnormal heart rhythm); or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you, and may adjust the dose as needed.

    • How should I take this medication?

      Take quinidine exactly as prescribed by your healthcare provider. Do not change your dose or stop taking quinidine without first talking to your healthcare provider.

    • What should I avoid while taking this medication?

      Do not chew or crush quinidine tablets without first checking with your healthcare provider. Chewing or crushing the tablets may prevent the medicine from releasing into your body throughout the day.

      Do not drink grapefruit juice while you are taking quinidine.

    • What are the possible food and drug interactions associated with this medication?

      If quinidine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Quinidine may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of quinidine during pregnancy are unknown. Quinidine can be found in your breast milk if you take it while breastfeeding. Do not breastfeed while you are taking quinidine. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of quinidine, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
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