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Ranexa is a medicine used alone or with other medication to treat long-term angina (chest pain). Ranexa is an extended-release medicine (a type of tablet that releases medicine into your body throughout the day).
How does this medication work?
It is unknown exactly how Ranexa works to relieve chest pain.
Ranexa is not used to treat an acute angina attack.
What are the beneficial effects of this medication and when should I begin to have results?
What: Ranexa has been shown to reduce chest pain associated with exercise and reduce angina attacks.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Ranexa exactly as your healthcare provider has prescribed.
How do I know it is working?
You may feel an improvement in your chest pain after you start taking Ranexa. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
More common side effects may include: dizziness, headache, constipation, nausea.
Less common side effects may include:
Changes in the electrical activity of your heart with symptoms such as feeling faint or lightheaded or fast, irregular heartbeats.
Ranexa can also cause or worsen existing kidney problems.
Do not take Ranexa if you are allergic to it or any of its ingredients.
Do not take Ranexa if you are taking certain medications such as carbamazepine, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, phenobarbital, phenytoin, rifabutin, rifampin, rifapentine, ritonavir, saquinavir, or St. John's wort.
Do not take Ranexa if you have liver cirrhosis (scarring of the liver).
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Ranexa. Also, talk to your healthcare provider about your complete medical history, especially if you have a heart problem called "long QT syndrome", liver or kidney problems, or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The usual starting dose is 500 milligrams (mg) twice a day. Your healthcare provider may increase your dose as needed, based on your condition and response.
Take Ranexa exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Ranexa without first talking to your healthcare provider.
Take Ranexa tablets whole, with or without food. Do not crush, break, or chew Ranexa tablets.
Do not drink or eat grapefruit juice or grapefruits while you are taking Ranexa.
Do not drive a car, operate heavy machinery, or engage in other dangerous activities until you know how Ranexa affects you.
If Ranexa is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Ranexa may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
The effects of Ranexa during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Ranexa, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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