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Ranitidine is a medicine used to treat and maintain healing of duodenal and gastric ulcers and erosive esophagitis (inflammation of the small intestine). Ranitidine is also used to treat gastroesophageal reflux disease (GERD) (a condition in which the stomach contents leak backwards from the stomach into the esophagus [the tube that connects your mouth and stomach]) and certain conditions where your stomach makes too much acid, such as Zollinger-Ellison syndrome. Ranitidine is available as tablets and capsules.
How does this medication work?
Ranitidine works by decreasing the amount of acid made in the stomach, thereby improving your symptoms.
What are the beneficial effects of this medication and when should I begin to have results?
Ulcers: Ranitidine may help heal and reduce the frequency and severity of pain associated with duodenal or gastric ulcers.
Erosive Esophagitis: Ranitidine has been shown to relieve heartburn associated with this condition.
GERD: By reducing stomach acid, ranitidine may help heal acid-related damage to the lining of your esophagus and relieve symptoms such as heartburn.
Conditions Causing Increased Stomach Acid Production: Ranitidine may reduce the acid produced in the stomach, thereby relieving symptoms associated with this condition.
When: Symptoms associated with GERD and erosive esophagitis may be relieved within 24 hours after starting treatment with ranitidine. However, everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take ranitidine exactly as your healthcare provider has prescribed.
How do I know it is working?
You may feel an improvement in your symptoms once you begin taking ranitidine. This is a good indicator that your medication is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Side effects may include: dizziness, drowsiness, slow or fast heartbeat, constipation, diarrhea, nausea, vomiting, joint or muscle pain, rash.
Do not take ranitidine if you are allergic to it or any of its ingredients.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with ranitidine. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems, porphyria (a blood disorder), or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Treatment of Duodenal Ulcers
Adults: The recommended dose is 150 milligrams (mg) twice a day. You may also take 300 mg once a day after your evening meal or at bedtime.
Children 1 month-16 years: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her weight.
Maintain Healing of Duodenal Ulcers and Gastric Ulcers
Adults: The recommended dose is 150 mg at bedtime.
Conditions Causing Increased Stomach Acid Production (Such as Zollinger-Ellison Syndrome) and Maintain Healing of Erosive Esophagitis
Adults: The recommended dose is 150 mg twice a day.
Treatment of Gastric Ulcer and GERD
Treatment of Erosive Esophagitis
Adults: The recommended dose is 150 mg four times a day.
If you have kidney impairment, your healthcare provider may adjust your dose appropriately.
Take ranitidine exactly as prescribed by your healthcare provider.
Your healthcare provider may prescribe antacids as needed for pain relief. Always follow your healthcare provider's instructions.
Do not change your dose or stop taking ranitidine without first talking to your healthcare provider.
If ranitidine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining ranitidine with the following: atazanavir, delavirdine, gefitinib, glipizide, ketoconazole, midazolam, procainamide, triazolam, or warfarin.
The effects of ranitidine during pregnancy are unknown. Ranitidine can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of ranitidine, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature, in a dry place. Protect from light.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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