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  • Generic Name: (silodosin)
    Other Brands: Rapaflo
  • Last Revised: 10/2013
    • What is this medication and its most common uses?

      Rapaflo is a medicine used to treat signs and symptoms of benign prostatic hyperplasia (BPH), a condition that may be referred to as an enlarged prostate.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Rapaflo works by relaxing the muscles in the prostate and bladder, thereby allowing urine to flow easily.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Rapaflo has been shown to improve symptoms of BPH, such as urinating frequently, strong urges to urinate, waking up to urinate, trouble urinating, incomplete bladder emptying, urinary flow that starts and stops, and a weak stream.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Rapaflo exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order tests regularly and ask you questions from time to time to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: problems with ejaculation, dizziness, diarrhea, sudden decrease in blood pressure, headache, common cold, nasal congestion.

      Less common side effects may include:

      A sudden drop in your blood pressure upon standing, especially at the start of treatment, with symptoms such as fainting, dizziness, or lightheadedness.

      Rapaflo may also cause eye problems during cataract surgery.

    • Who should not take this medication?

      Do not take Rapaflo if you are allergic to it or any of its ingredients.

      Do not take Rapaflo if you have severe kidney or liver impairment.

      Do not take Rapaflo if you are currently taking ketoconazole, clarithromycin, itraconazole, or ritonavir.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Rapaflo. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems, low blood pressure, prostate cancer, or plan to have cataract surgery.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 8 milligrams once a day.

      If you have kidney impairment, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Take Rapaflo exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Rapaflo without first talking to your healthcare provider.

      Take Rapaflo with a meal.

      If you have difficulty swallowing Rapaflo capsules, you may open the capsule and sprinkle the powder inside on a tablespoonful of applesauce. The applesauce should be swallowed immediately (within 5 minutes) without chewing, and followed by a glass of cool water. The applesauce should not be hot and it should be soft enough to be swallowed without chewing.

    • What should I avoid while taking this medication?

      Do not drive, operate machinery, or engage in other dangerous activities until you know how Rapaflo affects you.

    • What are the possible food and drug interactions associated with this medication?

      If Rapaflo is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Rapaflo with the following: blood pressure medications, cyclosporine, diltiazem, erythromycin, itraconazole, ketoconazole, medications for erectile dysfunction (an inability to attain or maintain an erection) (such as sildenafil or tadalafil), ritonavir, or verapamil.

    • May I receive this medication if I am pregnant or breastfeeding?

      Rapaflo is not for use in women.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Rapaflo, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature. Protect from light and moisture.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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