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  • Generic Name: (nitroglycerin)
    Other Brands:
  • Last Revised: 01/2014
    • What is this medication and its most common uses?

      Rectiv is a medicine used to treat pain caused by long-term anal fissures (a tear in the skin lining the anal canal). Rectiv is available as an ointment.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Rectiv works by relaxing the blood vessels in the anal canal, thereby helping to relieve your pain.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Rectiv has been shown to relieve your pain associated with anal fissures.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use Rectiv exactly as your healthcare provider has prescribed.

      How do I know it is working?

      You may feel an improvement in your pain after you start using Rectiv. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions to assess how well your symptoms are controlled.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: headache, dizziness.

      Less common side effects may include:

      Rectiv may lower your blood pressure.

    • Who should not take this medication?

      Do not use Rectiv if you are allergic to it, any of its ingredients, or to other similar medicines (such as isosorbide mononitrate).

      Do not use Rectiv if you are taking medicines for erectile dysfunction (an inability to attain or maintain an erection) (such as sildenafil, tadalafil, or vardenafil).

      Do not use Rectiv if you have anemia (low red blood cell counts).

      Do not use Rectiv if you have high pressure within your skull (following a head trauma or bleeding in your brain).

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Rectiv. Also, talk to your healthcare provider about your complete medical history, especially if you have low blood pressure; recently had a heart attack; have heart or blood vessel disorders; suffer from migraines or recurrent headaches; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Apply 1 inch of ointment around the inner sides of the anal canal every 12 hours.

    • How should I take this medication?

      Use Rectiv exactly as prescribed by your healthcare provider. Do not change your dose or stop using Rectiv without first talking to your healthcare provider.

      If you do not see an improvement in your condition in 3 weeks, call your healthcare provider.

      Please review the instructions that came with your prescription on how to properly apply Rectiv.

    • What should I avoid while taking this medication?

      Do not drive, operate heavy machinery, or do other dangerous activities until you know how Rectiv affects you.

      Do not drink alcohol while you are using Rectiv.

    • What are the possible food and drug interactions associated with this medication?

      If Rectiv is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Rectiv with the following: alcohol, aspirin, blood pressure/heart medications (such as metoprolol or amlodipine), erectile dysfunction medicines, ergotamine, heparin, or if you are receiving tissue-type plasminogen activator (t-PA) therapy (medicines used to help dissolve blood clots formed in the blood vessels in your heart, lungs, or brain).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Rectiv during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Rectiv, apply it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not apply two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.