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Reglan tablets contain a medicine used for the short-term treatment of gastroesophageal reflux disease (GERD) (a condition in which the stomach contents leak backwards from the stomach into the esophagus [the tube that connects your mouth and stomach]) in people who do not respond to other medicines. Reglan tablets are also used to relieve symptoms associated with diabetic gastroparesis (slow stomach emptying in people with diabetes).
How does this medication work?
Reglan tablets work by speeding the movement of food through the stomach and intestines.
What are the beneficial effects of this medication and when should I begin to have results?
What: Reglan tablets may help heal acid-related damage to the lining of your esophagus and relieve symptoms such as heartburn.
When: Reglan tablets may start working within 30 to 60 minutes.
How do I know it is working?
You may notice an improvement in your symptoms after you start taking Reglan tablets. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions from time to time to assess how well your symptoms are controlled.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Reglan tablets can cause a serious movement disorder called tardive dyskinesia (abnormal muscle movements, including tremor, shuffling, and uncontrolled, involuntary movements). The risk of developing tardive dyskinesia increases with duration of treatment and the total dose. If you experience any abnormal muscle movements, call your healthcare provider right away. Your healthcare provider may tell you to stop taking Reglan tablets. Do not take Reglan tablets for longer than 12 weeks, as directed by your healthcare provider.
More common side effects may include: restlessness, drowsiness, tiredness, lack of energy.
Less common side effects may include:
Involuntary movements, usually occurring during the first 24 to 48 hours of treatment, with symptoms such as uncontrolled spasms of your face and neck muscles, or muscles of your body, arms, and legs.
Symptoms similar to Parkinson's disease, such as slight shaking, body stiffness, or trouble moving or keeping your balance.
Neuroleptic malignant syndrome (a life-threatening brain disorder) with symptoms such as high fever, excessive sweating, muscle rigidity, confusion, changes in your breathing, fast or irregular heartbeat, or changes in your blood pressure.
Reglan tablets may also cause depression or suicidal thoughts.
Do not take Reglan tablets if you are allergic to them or any of their ingredients.
Do not take Reglan tablets if you have stomach or intestinal problems that could get worse with this medicine (such as bleeding, blockage, or a tear in the stomach or intestinal wall).
Do not take Reglan tablets if you have pheochromocytoma (a tumor of the adrenal gland).
Do not take Reglan tablets if you have seizures, or take certain medicines that can cause uncontrolled movements (such as fluphenazine).
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Reglan tablets. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney, liver, or heart problems; diabetes; depression; high blood pressure; Parkinson's disease; a history of breast cancer; or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: The recommended dose is 10 to 15 milligrams (mg) up to four times a day (30 minutes before each meal and at bedtime), as directed by your healthcare provider. Your healthcare provider may prescribe a different dose for you, based on the severity of your condition.
Symptoms of Diabetic Gastroparesis
Adults: The recommended dose is 10 mg 30 minutes before each meal and at bedtime, for 2 to 8 weeks, as directed by your healthcare provider.
If you are elderly or have kidney impairment, your healthcare provider may adjust your dose appropriately.
Take Reglan tablets exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Reglan tablets without first talking to your healthcare provider.
Do not drive, operate machinery, or engage in other dangerous activities until you know how Reglan tablets affect you.
Do not drink alcohol while taking Reglan tablets.
If Reglan tablets are taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Reglan tablets with the following: acetaminophen; alcohol; anticholinergics (such as atropine or ipratropium); certain antibiotics (such as tetracycline); certain diabetes medicines (such as insulin); cyclosporine; digoxin; levodopa; monoamine oxidase inhibitors (MAOIs), a class of medications used to treat depression and other conditions (such as phenelzine or tranylcypromine); narcotic painkillers (such as hydrocodone or oxycodone); sedatives; or tranquilizers (such as chlordiazepoxide).
The effects of Reglan tablets during pregnancy are unknown. The ingredients of Reglan tablets can be found in your breast milk if you take them while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Reglan tablets, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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