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  • Generic Name: (metoclopramide)
    Other Brands: N/A
  • Last Revised: 03/2014
    • What is this medication and its most common uses?

      Reglan tablets contain a medicine used for the short-term treatment of gastroesophageal reflux disease (GERD) (a condition in which the stomach contents leak backwards from the stomach into the esophagus [the tube that connects your mouth and stomach]) in people who do not respond to other medicines. Reglan tablets are also used to relieve symptoms associated with diabetic gastroparesis (slow stomach emptying in people with diabetes).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Reglan tablets work by speeding the movement of food through the stomach and intestines.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Reglan tablets may help heal acid-related damage to the lining of your esophagus and relieve symptoms such as heartburn.

      When: Reglan tablets may start working within 30 to 60 minutes.

      How do I know it is working?

      You may notice an improvement in your symptoms after you start taking Reglan tablets. This is a good indicator that the medicine is working. Your healthcare provider may ask you questions from time to time to assess how well your symptoms are controlled.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Reglan tablets can cause a serious movement disorder called tardive dyskinesia (abnormal muscle movements, including tremor, shuffling, and uncontrolled, involuntary movements). The risk of developing tardive dyskinesia increases with duration of treatment and the total dose. If you experience any abnormal muscle movements, call your healthcare provider right away. Your healthcare provider may tell you to stop taking Reglan tablets. Do not take Reglan tablets for longer than 12 weeks, as directed by your healthcare provider.

      More common side effects may include: restlessness, drowsiness, tiredness, lack of energy.

      Less common side effects may include:

      Involuntary movements, usually occurring during the first 24 to 48 hours of treatment, with symptoms such as uncontrolled spasms of your face and neck muscles, or muscles of your body, arms, and legs.

      Symptoms similar to Parkinson's disease, such as slight shaking, body stiffness, or trouble moving or keeping your balance.

      Neuroleptic malignant syndrome (a life-threatening brain disorder) with symptoms such as high fever, excessive sweating, muscle rigidity, confusion, changes in your breathing, fast or irregular heartbeat, or changes in your blood pressure.

      Reglan tablets may also cause depression or suicidal thoughts.

    • Who should not take this medication?

      Do not take Reglan tablets if you are allergic to them or any of their ingredients.

      Do not take Reglan tablets if you have stomach or intestinal problems that could get worse with this medicine (such as bleeding, blockage, or a tear in the stomach or intestinal wall).

      Do not take Reglan tablets if you have pheochromocytoma (a tumor of the adrenal gland).

      Do not take Reglan tablets if you have seizures, or take certain medicines that can cause uncontrolled movements (such as fluphenazine).

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Reglan tablets. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney, liver, or heart problems; diabetes; depression; high blood pressure; Parkinson's disease; a history of breast cancer; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.


      Adults: The recommended dose is 10 to 15 milligrams (mg) up to four times a day (30 minutes before each meal and at bedtime), as directed by your healthcare provider. Your healthcare provider may prescribe a different dose for you, based on the severity of your condition.

      Symptoms of Diabetic Gastroparesis

      Adults: The recommended dose is 10 mg 30 minutes before each meal and at bedtime, for 2 to 8 weeks, as directed by your healthcare provider.

      If you are elderly or have kidney impairment, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Take Reglan tablets exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Reglan tablets without first talking to your healthcare provider.

    • What should I avoid while taking this medication?

      Do not drive, operate machinery, or engage in other dangerous activities until you know how Reglan tablets affect you.

      Do not drink alcohol while taking Reglan tablets.

    • What are the possible food and drug interactions associated with this medication?

      If Reglan tablets are taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Reglan tablets with the following: acetaminophen; alcohol; anticholinergics (such as atropine or ipratropium); certain antibiotics (such as tetracycline); certain diabetes medicines (such as insulin); cyclosporine; digoxin; levodopa; monoamine oxidase inhibitors (MAOIs), a class of medications used to treat depression and other conditions (such as phenelzine or tranylcypromine); narcotic painkillers (such as hydrocodone or oxycodone); sedatives; or tranquilizers (such as chlordiazepoxide).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Reglan tablets during pregnancy are unknown. The ingredients of Reglan tablets can be found in your breast milk if you take them while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Reglan tablets, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.