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  • Generic Name: (eletriptan hydrobromide)
    Other Brands: Relpax
  • Last Revised: 07/2014
    • What is this medication and its most common uses?

      Relpax is a medicine used to treat migraine attacks with or without aura (vision, hearing, or movement disturbances).

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      A migraine occurs when swollen blood vessels in the brain press on nearby nerves. Relpax works by narrowing those blood vessels, helping to improve your migraine symptoms.

      This medicine is not used to prevent migraine attacks. Always follow the instructions your healthcare provider gave you for preventing migraines.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: In addition to reducing headache pain, Relpax has been shown to decrease migraine-associated symptoms, such as nausea and sensitivity to light and sound.

      When: Relpax may relieve your migraine pain within 2 hours.

      How do I know it is working?

      You may feel relief in your migraine headache after you take Relpax. This is a good indicator that the medicine is working. Recording your headache frequency and medication use may be helpful to you and your healthcare provider in monitoring your progress.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: weakness, nausea, dizziness, drowsiness.

      Less common side effects may include:

      Heart attack or other heart problems, with symptoms such as discomfort in the center of your chest that lasts for more than a few minutes or that goes away and comes back; chest pain or discomfort that feels like heavy pressure, squeezing, or fullness; pain or discomfort in your arms, back, neck, jaw, or stomach; shortness of breath with or without chest discomfort; breaking out in a cold sweat; nausea or vomiting; or lightheadedness.

      Bleeding in the brain or stroke, with symptoms such as numbness or weakness in your face, arm, or leg, especially on one side of your body; confusion; problems speaking or understanding; problems seeing in one or both of your eyes; problems walking; dizziness; loss of balance or coordination; or severe headache with no known cause.

      Stomach or intestinal problems, with symptoms such as sudden or severe stomach pain, stomach pain after meals, weight loss, nausea or vomiting, constipation or diarrhea, bloody diarrhea, or fever.

      Problems with blood circulation to your legs or feet, with symptoms such as cramping and pain in your legs or hips; feeling of heaviness or tightness in your leg muscles; burning or aching pain in your feet or toes while resting; cold feeling or color changes in one or both legs or feet; or numbness, tingling, or weakness in your legs.

      Serotonin syndrome (a potentially life-threatening drug reaction that causes the body to have too much serotonin, a chemical produced by the nerve cells) with symptoms such as mental status changes (such as agitation or hallucinations), an increase in your heart rate and body temperature, changes in your blood pressure, lack of coordination, overactive reflexes, muscle rigidity, nausea, vomiting, or diarrhea.

      Relpax may also cause arrhythmias (a life-threatening irregular heartbeat).

    • Who should not take this medication?

      Do not take Relpax if you are allergic to it or any of its ingredients.

      Do not take Relpax if you have a history of heart problems, stroke or "mini-stroke," problems with your blood circulation, or narrowing of blood vessels to your legs, arms, or stomach.

      Do not take Relpax if you have high blood pressure that is not controlled with medications.

      Do not take Relpax if you have taken similar medicines (such as rizatriptan, sumatriptan, or zolmitriptan) or ergot-containing medicines (such as ergotamine, dihydroergotamine, or methysergide) within the last 24 hours.

      Do not take Relpax if you have taken ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, or nelfinavir within the last 72 hours.

      Do not take Relpax if you have certain types of migraines known as hemiplegic or basilar migraines.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Relpax. Also, talk to your healthcare provider about your complete medical history, especially if you have high blood pressure; high cholesterol (fats in your blood) levels; diabetes; heart problems or a family history of heart disease or stroke; are a female who has gone through menopause; if you smoke or are overweight; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 20 milligrams (mg) or 40 mg, as directed by your healthcare provider. If your migraine has not gone away by 2 hours after taking Relpax, or if it is relieved after the first dose but comes back, you can take a second dose at least 2 hours after the first dose. Do not take more than 80 mg in 24 hours.

    • How should I take this medication?

      Take Relpax exactly as prescribed by your healthcare provider. Do not change your dose without first talking to your healthcare provider.

    • What should I avoid while taking this medication?

      Do not drive a car, operate heavy machinery, or engage in other activities that require you to be alert until you know how Relpax affects you.

    • What are the possible food and drug interactions associated with this medication?

      If Relpax is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Relpax may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Relpax during pregnancy are unknown. Relpax can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      Relpax should be taken only as needed for migraine attacks.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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