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  • Generic Name: (ropinirole)
    Other Brands: N/A
  • Last Revised: 10/2016
    • What is this medication and its most common uses?

      Requip is a medicine used to treat Parkinson's disease and restless legs syndrome.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Dopamine is a natural chemical in the brain that helps control movement. Requip is thought to increase the activity of dopamine, thereby improving motor control.

      What are the beneficial effects of this medication and when should I begin to have results?


      Parkinson's Disease: Studies show that people who receive Requip have significantly greater improvement in motor function (such as decreased muscle rigidity) than people who do not receive Requip.

      Restless Legs Syndrome: Requip has been shown to reduce the severity of symptoms, sleep disturbances, daytime drowsiness, and impact on activities of daily living, as measured by appropriate symptom rating scales that are commonly used by healthcare providers to evaluate the effectiveness of the medicine in people with such conditions.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Requip exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may ask you a series of questions from time to time, which will help assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Early Parkinson's Disease

      More common side effects may include: nausea, dizziness, drowsiness, vomiting, fainting, infection, leg swelling, upset stomach, weakness.

      Advanced Parkinson's Disease

      More common side effects may include: uncontrollable muscle movements, nausea, dizziness, confusion, drowsiness, headache, hallucinations, sweating.

      Restless Legs Syndrome

      More common side effects may include: nausea, drowsiness, vomiting, dizziness, weakness.

      Less common side effects of Requip may include:

      Falling asleep while doing normal activities such as driving a car, doing physical tasks, or using hazardous machinery. You may suddenly fall asleep without being drowsy or without warning. Your chances of falling asleep while doing normal activities while taking Requip are greater if you are also taking other medicines that cause drowsiness.

      Sudden fall in blood pressure when first standing up from sitting or lying down, especially when you start taking Requip or when your healthcare provider increases your dose, with symptoms such as dizziness, nausea, faintness, or sweating.

      Urges to behave in a way unusual for you, such as unusual urges to gamble or increased sexual urges and behaviors.

      If you are also taking L-dopa for Parkinson's disease, Requip may make some side effects of L-dopa worse, such as causing uncontrolled sudden movements or make such movement you already have worse.

      Requip may increase or decrease your heart rate.

      Requip can cause or worsen psychotic-like behavior including hallucinations (seeing or hearing things that are not real), confusion, excessive suspicion, aggressive behavior, agitation, delusional beliefs (believing things that are not real), and disorganized thinking.

      People with Parkinson's disease have a higher risk of melanoma (type of skin cancer). It is not clear if this risk is associated with the disease or with the medicines to treat it. Your healthcare provider may check your skin on regular basis.

    • Who should not take this medication?

      Do not take Requip if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Requip. Also, talk to your healthcare provider about your complete medical history, especially if you have liver or heart problems, changes in your blood pressure, daytime sleepiness from a sleep disorder other than restless legs syndrome, if you start or stop smoking, drink alcoholic beverages, or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Parkinson's Disease

      Adults: The recommended starting dose is 0.25 milligrams (mg) three times a day.

      Restless Legs Syndrome

      Adults: The recommended starting dose is 0.25 mg once a day, 1 to 3 hours before bedtime.

      If you have kidney impairment and are receiving dialysis, your healthcare provider may start you on a different dose.

      Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

    • How should I take this medication?

      People with restless legs syndrome take Requip differently than people with Parkinson's disease. Therefore, it is very important that you take Requip exactly as prescribed by your healthcare provider. Do not change your dose or suddenly stop taking Requip without first talking to your healthcare provider.

      Take Requip with or without food.

    • What should I avoid while taking this medication?

      Do not drive a car, operate machinery, or engage in other dangerous activities if you fall asleep or feel very sleepy after taking Requip.

    • What are the possible food and drug interactions associated with this medication?

      If Requip is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Requip may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Requip during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Requip, contact your healthcare provider.

    • How should I store this medication?

      Store at room temperature. Protect from light and moisture.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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