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Selzentry is a medicine used with other anti-HIV medicines to treat a certain type of HIV-1 infection.
How does this medication work?
Selzentry works by blocking the interaction of certain chemicals in your body that allows for HIV-1 to multiply, thereby lowering the amount of HIV-1 in your blood.
Selzentry does not cure HIV-1 infection or AIDS, and you may continue to experience illnesses associated with HIV-1 infection. See your healthcare provider regularly.
What are the beneficial effects of this medication and when should I begin to have results?
What: When used with other anti-HIV medicines, Selzentry may reduce the amount of HIV-1 in your blood and increase the number of white blood cells, thereby helping to fight off infections.
When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's instructions. It is important that you take Selzentry exactly as your healthcare provider has prescribed.
How do I know it is working?
Your healthcare provider may order tests regularly to check how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Selzentry can cause serious liver problems. Tell your healthcare provider immediately if you experience symptoms such as dark-colored urine, yellowing of your skin or the whites of your eyes, an itchy rash on your body, vomiting, or upper right stomach area pain. Your healthcare provider will order periodic blood tests to check your liver function during your treatment with Selzentry.
More common side effects may include: upper respiratory infection, cough, fever, rash, dizziness.
Less common side effects may include:
Serious skin rash and allergic reactions, with symptoms such as fever; generally ill feeling; muscle aches; blisters or sores in your mouth; blisters or peeling of the skin; swelling of the mouth, face, or lips; problems breathing; yellowing of the skin or whites of your eyes; dark- or tea-colored urine; pain, aching, or tenderness on the right side below the ribs; loss of appetite; nausea; or vomiting.
Heart problems including heart attack.
Sudden fall in blood pressure when first standing up from sitting or lying down.
Changes in your immune system, which gets stronger and begins to fight infections that have been hidden in your body for a long time, leading to new symptoms after starting HIV treatment.
Selzentry may also increase your risk of infection or cancer.
Do not take Selzentry if you are allergic to it or any of its ingredients.
Do not take Selzentry if you have severe kidney problems.
Do not take Selzentry if you are taking certain other medications.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Selzentry. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney, heart, or liver problems (including a history of hepatitis B or C); low blood pressure or take medicines to lower your blood pressure; or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: Your healthcare provider will prescribe the appropriate dose for you, based on the other medicines you take.
If you have kidney problems or are taking certain other medications, your healthcare provider may adjust your dose appropriately.
Take Selzentry exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Selzentry without first talking to your healthcare provider.
Take Selzentry twice a day, at the same time each day. Take it with or without food.
When your medicine starts to run low, get more from your healthcare provider or pharmacy. Do not run out of Selzentry. The virus in your blood may increase and the virus may become harder to treat.
Do not do anything that can spread HIV-1 to others, such as sharing needles or other injection equipment, sharing personal items that can have blood or body fluids on them (such as toothbrushes or razor blades), or having any kind of unprotected sex.
Do not drive a car, operate heavy machinery, or engage in other dangerous activities until you know how Selzentry affects you.
If Selzentry is taken with certain other drugs, the effects of either could be increased, decreased, or altered. Selzentry may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
The effects of Selzentry during pregnancy and breastfeeding are unknown. Mothers with HIV-1 should not breastfeed because HIV-1 can be passed to the baby in the breast milk. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you become pregnant while taking Selzentry, talk to your healthcare provider about registering with the Antiretroviral Pregnancy Registry. The purpose of this registry is to collect information about the safety of this medicine during pregnancy.
If you miss a dose of Selzentry, take it as soon as you remember. However, if it is less than 6 hours before your next scheduled dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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