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  • Generic Name: (acrivastine/pseudoephedrine hydrochloride)
    Other Brands: N/A
  • Last Revised: 06/2014
    • What is this medication and its most common uses?

      Semprex-D is a combination medicine used to relieve symptoms associated with seasonal allergies.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Semprex-D contains two medicines: acrivastine and pseudoephedrine. Acrivastine works by blocking the release of a chemical in your body called histamine that causes allergic symptoms. Pseudoephedrine works by narrowing the blood vessels in your nasal passages. Together, they help to improve your condition.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Semprex-D may improve allergy symptoms such as sneezing, runny nose, itching, watery eyes, or stuffy nose.

      When: Semprex-D may start working within 1 or 2 hours after taking the first dose.

      How do I know it is working?

      You may notice an improvement in your allergy symptoms after you start taking Semprex-D. This is a good indicator that the medicine is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Common side effects may include: drowsiness, headache.

    • Who should not take this medication?

      Do not take Semprex-D if you are allergic to it, any of its ingredients, or to similar medicines (such as triprolidine).

      Do not take Semprex-D if you have severe high blood pressure or coronary artery disease (narrowing of the small blood vessels that supply blood and oxygen to the heart).

      Do not take Semprex-D if you are taking another medicine known as a monoamine oxidase inhibitor (MAOI), a class of medications used to treat depression and other conditions (such as phenelzine or tranylcypromine). Do not start taking Semprex-D if you stopped taking an MAOI in the last 2 weeks.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Semprex-D. Also, talk to your healthcare provider about your complete medical history, especially if you have high blood pressure; diabetes; heart, thyroid, kidney, or prostate problems; increased pressure in your eye; stomach problems (such as an ulcer or intestinal blockage); or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults and adolescents ≥12 years: The recommended dose is one capsule every 4 to 6 hours or four times a day, as directed by your healthcare provider.

    • How should I take this medication?

      Take Semprex-D exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Semprex-D without first talking to your healthcare provider.

    • What should I avoid while taking this medication?

      Do not drive, operate machinery, or engage in other tasks requiring alertness until you know how Semprex-D affects you.

      Do not drink alcohol or take medicines that make you sleepy while taking Semprex-D.

    • What are the possible food and drug interactions associated with this medication?

      If Semprex-D is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Semprex-D with the following: alcohol, certain asthma medicines (such as albuterol), MAOIs, or medicines that make you sleepy (such as oxycodone or chlordiazepoxide).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Semprex-D during pregnancy are unknown. Semprex-D can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Semprex-D, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature, in a dry place. Protect from light.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
      time!
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