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  • Generic Name: (salmeterol xinafoate)
    Other Brands: N/A
  • Last Revised: 05/2014
    • What is this medication and its most common uses?

      Serevent Diskus is a medicine used to treat asthma and airway narrowing associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis (long-term inflammation of the lungs) and emphysema (lung disease that causes shortness of breath). Serevent Diskus is also used to prevent wheezing caused by exercise.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Serevent Diskus works by relaxing the muscles in your airways.

      This medication is not used for emergency or immediate treatment of symptoms of airway narrowing. Always have a short-acting rescue inhaler (such as albuterol) to treat sudden symptoms.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Serevent Diskus helps prevent symptoms of asthma and COPD, such as wheezing and shortness of breath. It may also help you breathe better while exercising.

      When: Serevent Diskus may start controlling your symptoms within 30 minutes of inhaling it.

      How do I know it is working?

      You may feel an improvement in your breathing once you begin using Serevent Diskus. Your healthcare provider may perform tests to check your lung function and ask you questions to assess how well your symptoms are controlled.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      If you have asthma and use Serevent Diskus, you can have an increased risk of death from asthma problems. Tell your healthcare provider if your breathing problems worsen over time while you are using Serevent Diskus. Get emergency medical care if your breathing problems worsen quickly or if you use your rescue inhaler medicine, but it does not relieve your symptoms.


      More common side effects may include: headache, flu, stuffy or runny nose, sore throat, bronchitis.


      More common side effects may include: cough, headache, muscle pain, throat irritation, respiratory infection.

      Less common side effects of Serevent Diskus may include:

      Sudden breathing problems right after inhaling your medicine.

      Effects on your heart or nervous system with symptoms such as increased blood pressure, fast or irregular heartbeat, chest pain, shaking, nervousness.

    • Who should not take this medication?

      Do not use Serevent Diskus if you are allergic to it, any of its ingredients, or to milk proteins.

      Do not use Serevent Diskus to treat sudden, severe symptoms of asthma or COPD (such as an asthma attack).

      Do not use Serevent Diskus to treat your asthma without an asthma medicine known as an inhaled corticosteroid (medicine that helps treat inflammation).

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Serevent Diskus. Also, talk to your healthcare provider about your complete medical history, especially if you have heart, thyroid, or liver problems; high blood pressure; seizures; or diabetes.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.


      Adults and children ≥4 years: The usual dose is 1 inhalation twice a day (about 12 hours apart).

      Prevention of Exercise-Induced Wheezing

      Adults and children ≥4 years: The usual dose is 1 inhalation at least 30 minutes before exercise. Do not use more often than every 12 hours.

      Do not use extra Serevent Diskus before exercise if you already use it twice a day.


      Adults: The usual dose is 1 inhalation twice a day (about 12 hours apart).

    • How should I take this medication?

      Use Serevent Diskus exactly as prescribed by your healthcare provider. Do not use it more often or stop using it without first talking to your healthcare provider.

      Please review the instructions that came with your prescription on how to properly use your inhaler.

    • What should I avoid while taking this medication?

      Do not use extra doses of Serevent Diskus if you do not feel or taste the medicine when you inhale it. Serevent Diskus delivers your dose of medicine as a very fine powder and you may not taste or feel it.

    • What are the possible food and drug interactions associated with this medication?

      If Serevent Diskus is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Serevent Diskus with the following: atazanavir, blood pressure/heart medications known as beta-blockers (such as propranolol), certain antidepressants (such as nortriptyline or phenelzine), clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or water pills (such as furosemide or hydrochlorothiazide).

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Serevent Diskus during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Serevent Diskus, skip that dose and return to your regular dosing schedule. Do not inhale two doses at once.

    • How should I store this medication?

      Store at room temperature, away from direct heat or sunlight.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
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