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  • Generic Name: (clomiphene citrate)
    Other Brands: Clomid
  • Last Revised: 04/2014
    • What is this medication and its most common uses?

      Serophene is a medicine used to treat problems with ovulation (the release of an egg from an ovary) in women who want to become pregnant.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Serophene works by stimulating ovulation (egg production), thereby increasing the chance of becoming pregnant.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Studies have shown that 30% of women treated with Serophene had successful pregnancies.

      When: Ovulation usually occurs 5 to 10 days after a course of Serophene. Sexual intercourse should be timed to coincide with the expected time of ovulation. It is important that you take Serophene exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how you are responding to treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: flushing (feeling of warmth on your skin), stomach discomfort, bloating, nausea, vomiting, breast tenderness.

      Less common side effects may include:

      Ovarian hyperstimulation syndrome (enlarged and swollen ovaries) with symptoms such as pelvic pain, difficulty breathing, decreased urine, low blood pressure, stomach bloating, nausea, vomiting, diarrhea, and weight gain.

      Changes in your vision with symptoms such as blurring and seeing spots or flashes.

      Increased chance of becoming pregnant with more than one baby (such as twins or triplets).

    • Who should not take this medication?

      Do not take Serophene if you are allergic to it or any of its ingredients.

      Do not take Serophene if you have unexplained vaginal bleeding (until a diagnosis is reached by your healthcare provider) or have cysts in your ovaries.

      Do not take Serophene if you have liver problems.

      Do not take Serophene if you have uncontrolled thyroid or adrenal dysfunction due to a brain tumor.

      Do not take Serophene if you are pregnant.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Serophene. Also, talk to your healthcare provider about your complete medical history, especially if you have liver problems, thyroid or adrenal gland problems, cancer, or if you are pregnant or breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Women: The usual starting dose is 50 milligrams once a day for 5 days. Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

    • How should I take this medication?

      Take Serophene exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Serophene without first talking to your healthcare provider.

      It is important to time the sexual intercourse correctly while you are ovulating. Your healthcare provider may suggest helpful tools (such as a basal body temperature) and other appropriate tests to help you determine the correct timing.

    • What should I avoid while taking this medication?

      Do not drive a car, operate heavy machinery, or engage in other dangerous activities until you know how Serophene affects you.

    • What are the possible food and drug interactions associated with this medication?

      No significant interactions have been reported with Serophene at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

    • May I receive this medication if I am pregnant or breastfeeding?

      Do not take Serophene if you are already pregnant. The effects of Serophene during breastfeeding are unknown. Tell your healthcare provider if you are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Serophene, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature. Protect from heat, light, and excessive moisture.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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