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  • Generic Name: (methimazole)
    Other Brands: N/A
  • Last Revised: 01/2016
    • What is this medication and its most common uses?

      Tapazole is a medicine used to treat hyperthyroidism (an overactive thyroid gland). It is also used before thyroid surgery or radioactive iodine treatment.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      When you have hyperthyroidism, your thyroid gland makes too much thyroid hormone. Tapazole works by stopping the thyroid gland from making thyroid hormone, thereby helping to restore the balance in your body.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By restoring your thyroid hormone balance, Tapazole may help relieve your symptoms associated with high thyroid levels.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. Though you may not feel an improvement or change in the way you feel, it is very important to keep taking your medicine as prescribed to keep your condition under control.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: rash, hives, nausea, vomiting, abdominal (stomach area) pain, joint or muscle pain, tingling or numbness of your hands or feet, loss of taste, abnormal loss of hair, headache, itching, drowsiness, swelling, a spinning feeling, changes in your skin color, yellowing of your skin or the whites of your eyes.

      Less common side effects may include:

      Agranulocytosis (a blood disorder in which white blood cells are not made in adequate numbers or not made at all), with symptoms such as fever or sore throat.

      Liver problems, with symptoms such as loss of appetite, itching, or right upper abdominal pain.

      Harm to your unborn baby during the first few months of your pregnancy. Tell your healthcare provider immediately if you are pregnant or plan to become pregnant.

      Tapazole may cause hypothyroidism (an underactive thyroid gland).

    • Who should not take this medication?

      Do not take Tapazole if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Tapazole. Also, talk to your healthcare provider about your complete medical history, especially if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you, based on the severity of your condition.

      Children: Your healthcare provider will prescribe the appropriate dose for your child, based on his/her weight.

      Your healthcare provider may adjust your dose as needed, until the desired effect is achieved.

    • How should I take this medication?

      Take Tapazole exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Tapazole without first talking to your healthcare provider.

      Take Tapazole in three divided doses, about 8 hours apart.

    • What should I avoid while taking this medication?

      Do not miss any scheduled follow-up appointments with your healthcare provider.

    • What are the possible food and drug interactions associated with this medication?

      If Tapazole is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Tapazole with the following: blood pressure/heart medications known as beta-blockers (such as atenolol or metoprolol), blood thinners (such as warfarin), digoxin, or theophylline.

    • May I receive this medication if I am pregnant or breastfeeding?

      Tapazole may harm your unborn baby, especially if you take it during the first few months of pregnancy. Tapazole can be found in your breast milk if you take it while breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Tapazole, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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