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Targretin capsules are used to treat skin problems in people with a type of skin cancer called cutaneous T-cell lymphoma (CTCL) who have not responded to at least one other therapy.
How does this medication work?
Targretin capsules are thought to work by inhibiting the growth of cancer cells.
What are the beneficial effects of this medication and when should I begin to have results?
What: Targretin capsules may help reduce redness, scaling, plaque elevation, or changes in skin color associated with CTCL.
When: You may see an improvement in your skin within several weeks of starting treatment with Targretin capsules. However, everyone responds differently to treatment and most people require several months or more of treatment, so try to be patient and follow your healthcare provider's directions.
How do I know it is working?
You may start to notice an improvement in your skin after starting treatment with Targretin capsules. This is a good indicator that your medication is working. Your healthcare provider may examine your skin regularly to check how well this medication is working.
The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.
Targretin capsules may harm your unborn baby if taken during pregnancy. Contact your healthcare provider immediately if you believe or suspect you are pregnant while you are taking Targretin capsules and until one month after you stop taking them. If you are a woman of childbearing age, you must have a pregnancy test within one week before you start treatment with Targretin capsules and monthly while you are taking them. You must use effective birth control starting one month before you begin treatment with Targretin capsules until one month after you stop taking them. It is recommended that you use two reliable forms of birth control together. Targretin capsules may reduce the effectiveness of hormonal birth control. Therefore, it is recommended that one of the forms of birth control be nonhormonal (such as condoms). Men with sexual partners who are pregnant, possibly pregnant, or who could become pregnant must use condoms during sexual intercourse while taking Targretin capsules and for at least one month after the last dose.
More common side effects may include: increased cholesterol (fats in your blood) levels, headache, underactive thyroid, weakness, low white blood cell counts, rash, nausea, infection, swelling of your hands or feet, abdominal (stomach area) pain, dry skin.
Symptoms of underactive thyroid may include: excessive tiredness, low energy levels, or feeling unusually cold all the time.
Less common side effects may include:
Targretin capsules may cause pancreatitis (inflammation of the pancreas), liver problems, or cataracts.
Do not take Targretin capsules if you are allergic to them or any of their ingredients.
Do not take Targretin capsules if you are pregnant or plan to become pregnant.
Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Targretin capsules. Also, talk to your healthcare provider about your complete medical history, especially if you have liver, thyroid, or gallbladder problems; high cholesterol or triglyceride (type of fat in the blood) levels; diabetes; cataracts; history of pancreatitis; drink alcohol; or if you are pregnant, plan to become pregnant, or are breastfeeding.
The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.
Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your height and weight.
Take Targretin capsules exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Targretin capsules without first talking to your healthcare provider.
Take Targretin capsules as a single daily dose with a meal.
It is important that you limit the amount of vitamin A that you take during treatment with Targretin capsules. Talk to your healthcare provider about vitamin A intake.
Do not become pregnant while you are taking Targretin capsules.
Do not expose your skin to excessive sunlight and ultraviolet lights (such as sunlamps or tanning lamps) while taking Targretin capsules.
If Targretin capsules are taken with certain other drugs, the effects of either could be increased, decreased, or altered. Targretin capsules may interact with numerous medications. Therefore, it is very important that you tell your healthcare provider about any other medications you are taking.
Targretin capsules may harm your unborn baby if you take them during pregnancy. Do not take Targretin capsules if you are pregnant or breastfeeding. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
If you miss a dose of Targretin capsules, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.
Store at room temperature. Protect from light.
Do not expose Targretin capsules to high temperatures and humidity after the bottle is opened.
In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
National Poison Control#: Call 1-800-222-1222
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