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  • Generic Name: (tolcapone)
    Other Brands: N/A
  • Last Revised: 10/2015
    • What is this medication and its most common uses?

      Tasmar is a medicine used in combination with levodopa/carbidopa to treat Parkinson's disease.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Symptoms of Parkinson's disease may occur when there is a decrease in dopamine in the brain. Tasmar works by allowing a larger amount of a medicine called levodopa to reach the brain, thereby increasing dopamine levels.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Tasmar may help to improve mobility and symptoms associated with Parkinson's disease, such as shaking or rigidity.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Tasmar exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may ask you a series of questions from time to time that will help assess how well your symptoms are controlled with treatment.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Tasmar may cause life-threatening liver problems. Therefore, Tasmar should only be used in people with Parkinson's disease who are taking levodopa/carbidopa and are still experiencing symptoms. If you do not see an improvement in your condition within 3 weeks of starting treatment with Tasmar, your healthcare provider may stop prescribing Tasmar to you. Your healthcare provider may do certain liver function tests before starting you on Tasmar. If you previously experienced liver problems associated with Tasmar, notify your healthcare provider. Also, tell your healthcare provider if you experience symptoms such as nausea, tiredness, loss of appetite, yellowing of your skin or the whites of your eyes, dark urine, itching, or right upper stomach tenderness.

      More common side effects may include: involuntary muscle movements, nausea, diarrhea, loss of appetite, sleep disorder, vomiting, urine discoloration, drowsiness, hallucinations, sweating.

      Less common side effects may include:

      Sudden fall in your blood pressure with symptoms such as dizziness, nausea, sweating, or fainting when rising too quickly from a sitting or lying position.

      Changes in your behavior, such as intense urges to gamble, increased sexual urges, or other intense urges.

      Tasmar may also cause hallucinations, muscle pain, fever, confusion, or an increased risk of skin cancer.

    • Who should not take this medication?

      Do not take Tasmar if you are allergic to it or any of its ingredients.

      Do not take Tasmar if you previously experienced liver problems associated with Tasmar.

      Do not take Tasmar if you have severe muscle pain, fever, or confusion that may be associated with Tasmar.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Tasmar. Also, talk to your healthcare provider about your complete medical history, especially if you have kidney or liver problems.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: The recommended dose is 100 milligrams three times a day.

      It is important that you do not stop taking this medication abruptly. If you need to change or stop taking this medication, it is important that you only do this with the guidance of your healthcare provider.

    • How should I take this medication?

      Take Tasmar exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Tasmar without first talking to your healthcare provider.

      Take Tasmar with or without food.

    • What should I avoid while taking this medication?

      Do not drive, operate heavy machinery, or do other dangerous activities until you know how Tasmar affects you.

    • What are the possible food and drug interactions associated with this medication?

      If Tasmar is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Tasmar with the following: a certain type of monoamine oxidase inhibitor (MAOI) (such as phenelzine or tranylcypromine), a class of medications used to treat depression and other conditions; apomorphine; desipramine; methyldopa; or warfarin.

    • May I receive this medication if I am pregnant or breastfeeding?

      The effects of Tasmar during pregnancy and breastfeeding are unknown. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Tasmar, take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.