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  • Generic Name: (mechlorethamine)
    Other Brands: N/A
  • Last Revised: 12/2014
    • What is this medication and its most common uses?

      Valchlor is a medicine used to treat mycosis fungoides-type lymphoma (a type of cancer of the immune system that first appears as skin rashes). Valchlor is available as a gel.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Valchlor is thought to work by slowing or stopping the growth of cancer cells in the body.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: By stopping the growth of cancer cells, Valchlor may help to relieve your symptoms associated with cancer.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you use Valchlor exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      More common side effects may include: redness, swelling, itching, skin ulcers or blisters, skin infection, darkening areas of your skin.

      Less common side effects may include:

      Eye injury if exposed to the eyes, with symptoms such as pain, burns, swelling, double vision, or blurry vision.

      Risk of secondary exposure, with symptoms such as swelling of the skin; injury to the eyes, mouth, or nose; or certain types of cancers.

      Increased risk of certain types of skin cancers.

      Harm to your unborn baby. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • Who should not take this medication?

      Do not use Valchlor if you are allergic to it or any of its ingredients.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Valchlor. Also, talk to your healthcare provider about your complete medical history, especially if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Apply a thin film to the affected area(s) once a day.

      Your healthcare provider may adjust your dose as needed, until the desired effects are achieved.

    • How should I take this medication?

      Apply Valchlor exactly as prescribed by your healthcare provider. Do not use it more often or stop using it without first talking to your healthcare provider.

      Apply Valchlor right away or within 30 minutes after you take it out of the refrigerator. Return to the refrigerator right after each use.

      Apply Valchlor to completely dry skin at least 4 hours before or 30 minutes after showering or washing. Let the treated area dry for 5 to 10 minutes after applying Valchlor before covering with clothing.

      Wash your hands thoroughly with soap and water after handling or applying Valchlor.

      If you are a caregiver, wear disposable nitrile gloves, and wash your hands thoroughly with soap and water after removal of gloves.

      You may use moisturizers to the treated areas 2 hours before or 2 hours after applying Valchlor.

      If you get Valchlor in your eyes, mouth, or nose, immediately irrigate for at least 15 minutes with water, and notify your healthcare provider right away.

    • What should I avoid while taking this medication?

      Do not go near fire, flame, and smoking until Valchlor has dried completely.

      Do not use air or water-tight bandages on areas of the skin treated with Valchlor.

    • What are the possible food and drug interactions associated with this medication?

      No significant interactions have been reported with Valchlor at this time. However, always tell your healthcare provider about any medicines you take, including over-the-counter medications, vitamins, and herbal supplements.

    • May I receive this medication if I am pregnant or breastfeeding?

      Valchlor can harm your unborn baby if you use it during pregnancy. The effects of Valchlor during breastfeeding are unknown. Do not breastfeed while you are using Valchlor. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Valchlor, use it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular dosing schedule. Do not use two doses at once.

    • How should I store this medication?

      Store in the refrigerator.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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    This discount plan is NOT insurance or a Medicare prescription drug plan. The plan is not intended as a substitute for insurance and does not meet creditable coverage requirements under state or federal law. The plan provides discounts at participating pharmacies on certain pharmaceutical supplies, prescription drugs, or medical equipment and supplies. The range of discounts will vary depending on the products received. Members are obligated to pay the pharmacy the entire amount of the discounted rate for such products at the point of sale. The plan does not pay pharmacies for products provided to members. No enrollment or periodic fees apply. The pharmacy may pay the plan a fee from amounts the pharmacy collects from the member. The discount plan organization is ProCare Pharmacy Benefit Manager, Inc.,1267 Professional Parkway, ProCare Office Park, Gainesville, GA 30507, 1-888-299-5383. Customer service is provided by PDR, LLC., 5 Paragon Drive, Montvale, NJ, 07645, 1-800-232-7379, www.pdr.net/DiscountCard, customerservice@pdr.net.