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  • Generic Name: (capecitabine)
    Other Brands: N/A
  • Last Revised: 04/2015
    • What is this medication and its most common uses?

      Xeloda is an anticancer medicine used to treat colon cancer after surgery and colorectal (colon or rectum) cancer that has spread to other parts of the body. Xeloda is also used alone or in combination with docetaxel, to treat breast cancer that has spread to other parts of the body and cannot be treated with other medicines.

    • What should I know when beginning and continuing on this medication?

      How does this medication work?

      Xeloda works by inhibiting the growth of cancer cells, thereby reducing the tumor size.

      What are the beneficial effects of this medication and when should I begin to have results?

      What: Xeloda may decrease tumor size and improve symptoms.

      When: Everyone responds differently to treatment, so try to be patient and follow your healthcare provider's directions. It is important that you take Xeloda exactly as your healthcare provider has prescribed.

      How do I know it is working?

      Your healthcare provider may order tests regularly to check how well this medication is working.

    • What are the possible side effects of this medication?

      The following is not a full list of side effects. Side effects cannot be anticipated. If any develop or change in intensity, tell your healthcare provider as soon as possible. Only your healthcare provider can determine if it is safe for you to continue taking this medication.

      Xeloda can cause serious and life-threatening bleeding if taken together with certain blood thinner medications (such as warfarin). Your risk may be increased if you are >60 years old or have cancer. Your healthcare provider will monitor you during your treatment with Xeloda.

      More common side effects may include: diarrhea; nausea; vomiting; stomach area pain; hand-and-foot syndrome (condition with symptoms such as the palms of your hands or soles of your feet tingle, feel numb, or are painful, swollen, or red); tiredness, weakness.

      Less common side effects may include:

      Heart problems with symptoms such as chest pain, shortness of breath, feeling faint, irregular heartbeats or skipping beats, sudden weight gain, or swollen ankles or legs.

      Condition known as dihydropyrimidine dehydrogenase (DPD) deficiency with symptoms such as ulcers and inflammation of the linings of the stomach and intestines, diarrhea, and nerve damage.

      Low blood cell counts with symptoms such as easy bruising or bleeding, infection, fever, paleness, or unusual tiredness.

      Loss of too much body fluid (dehydration) and serious kidney problems with symptoms such as loss of appetite, weakness, nausea, vomiting, or diarrhea.

      Serious skin and mouth reactions with symptoms such as skin rash, blisters, peeling of your skin, or painful redness of your mouth and tongue.

      Xeloda may harm your unborn baby if you take it during pregnancy. Contact your healthcare provider immediately if you believe or suspect you are pregnant while you are taking Xeloda.

    • Who should not take this medication?

      Do not take Xeloda to you if you are allergic to it or any of its ingredients.

      Do not take Xeloda if you have serious kidney impairment.

    • What should I tell my healthcare provider before I take the first dose of this medication?

      Tell your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Xeloda. Also, talk to your healthcare provider about your complete medical history, especially if you have heart, kidney, or liver problems; if you lack the enzyme DPD; or if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What is the usual dosage?

      The information below is based on the dosage guidelines your healthcare provider uses. Depending on your condition and medical history, your healthcare provider may prescribe a different regimen. Do not change the dosage or stop taking your medication without your healthcare provider's approval.

      Adults: Your healthcare provider will prescribe the appropriate dose for you, based on your height and body weight.

      If you have kidney impairment, your healthcare provider may adjust your dose appropriately.

    • How should I take this medication?

      Take Xeloda exactly as prescribed by your healthcare provider. Do not change your dose or stop taking Xeloda without first talking to your healthcare provider.

      Take Xeloda within 30 minutes after a meal.

      Swallow Xeloda tablets whole with water. Do not cut or crush Xeloda tablets.

    • What should I avoid while taking this medication?

      Do not become pregnant or breastfeed while you are taking Xeloda. Men taking Xeloda should use effective birth control methods.

    • What are the possible food and drug interactions associated with this medication?

      If Xeloda is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your healthcare provider before combining Xeloda with the following: blood thinners (such as warfarin), folic acid, phenytoin, or leucovorin.

    • May I receive this medication if I am pregnant or breastfeeding?

      Xeloda can cause harm to your unborn baby if you take it during pregnancy. Do not become pregnant or breastfeed while you are taking Xeloda. Tell your healthcare provider immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

    • What should I do if I miss a dose of this medication?

      If you miss a dose of Xeloda, skip the one you missed and return to your regular dosing schedule. Do not take two doses at once.

    • How should I store this medication?

      Store at room temperature.

    • Who should I contact in case of emergency or overdose?
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      In the event of a medical emergency call your doctor or 9-1-1 immediately. In the event of overdose, call your doctor or poison control for further instructions.
      National Poison Control#: Call 1-800-222-1222

      This PDR+ drug information has been developed by the Physicians’ Desk Reference Network (PDRN), a source of medication information trusted by doctors for over 65 years.

      This monograph summarizes the most important information about your medication and does not cover all the information you may need. If you have any questions or concerns or want to learn more about your medication, ask your healthcare provider; he/she will be able to provide answers to your questions. This medication should only be used by the patient for whom it was prescribed and should not be shared with other people.
    • Additional patient resources.
      back to top Use your PDR® Pharmacy Discount Card when you or a family member fills a prescription and ask for your PDR® Discount every
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